News & Views in 2010

Machine learning reveals combinatorial patterns of transcription factor binding that drive gene expression.

New insights into the maize genome must be incorporated into breeding programs to realize the potential of crop genomics.

High-throughput measurements across several regulatory levels provide a comprehensive view of ES-cell differentiation.

A new metric called the normalized spectral index (SI_N) provides a simple way to quantify and compare label-free proteomics data.

Structural insights into the regulation of phosphodiesterase 4 lead to the discovery of allosteric modulators with reduced side effects.

Advances in technology deliver cheaper human genome sequencing.