Brassica oleracea pan-genome
Genome assemblies of 22 Brassica oleracea accessions and pan-genome analyses highlight the effects of structural variation on gene expression and its contribution to morphotype diversification.
Genome assemblies of 22 Brassica oleracea accessions and pan-genome analyses highlight the effects of structural variation on gene expression and its contribution to morphotype diversification.
We show that in addition to promoter activation, MYC drives cancer progression by activating transcriptional enhancers via a distinct mechanism. MYC cooperates with several other proteins at these cis-regulatory regions to change the epigenome and promote recruitment of RNA polymerase II and enhancer transcription.