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Volume 594 Issue 7864, 24 June 2021

Quantum compass

Many creatures use Earth’s magnetic field to help them navigate, but the exact nature of this internal compass has remained elusive. In this week’s issue, scientists from the Universities of Oxford and Oldenburg reveal the quantum properties of a protein that makes it a strong contender for the compass in migratory songbirds. The researchers examined the protein cryptochrome (ErCRY4), which is found in the retina of migratory European robins (Erithacus rubecula), and found that it could have the required level of magnetic sensitivity to act as a light-dependent compass. They identified that in vitro ErCRY4 undergoes a light-driven chemical reaction that triggers quantum effects that might enable sensing of magnetic signals. The team also found that the molecule in robins has greater magnetic sensitivity than the equivalent protein in non-migratory pigeons and chickens, leading them to conclude that it is likely to be a key component in the way robins navigate.

Cover image: Corinna Langebrake and Ilia Solov’yov

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    • How animals sense Earth’s magnetic field is an enduring mystery. The protein cryptochrome ErCRY4, found in the eyes of migratory European robins, has the right physical properties to be the elusive magnetosensor.

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      • Aashutosh Mistry
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    • As a blueprint for high-precision quantum simulation, an 18-qubit algorithm that consists of more than 1,400 two-qubit gates is demonstrated, and reconstructs the energy eigenvalues of the simulated one-dimensional wire to a precision of 1 per cent.

      • C. Neill
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      • Shuntaro Amano
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      Article
    • Cryptochrome 4 from the night-migratory European robin displays magnetically sensitive photochemistry in vitro, in which four successive flavin–tryptophan radical pairs generate magnetic-field effects and stabilize potential signalling states.

      • Jingjing Xu
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      Collection:

      Article
    • MARK4 regulates cardiomyocyte contractility by promoting MAP4 phosphorylation, which facilitates the access of VASH2 to microtubules for the detyrosination of α-tubulin; MARK4 deficiency after acute myocardial infarction limits the reduction in the left ventricular ejection fraction.

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    • Cryo-electron microscopy structures of homo- and heterodimers of mGlu2 and mGlu7 provide insights into their dimerization modes and the subunit conformational changes that characterize the activation of these class C G-protein-coupled receptors.

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    • Cryo-electron microscopy structure of heterodimeric GABAB receptor in complex with Gi1 protein reveals that the mode of G-protein binding in this class-C G-protein-coupled receptor differs from that of other classes.

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      Article Open Access
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