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Researchers can work long and hard for a permanent academic position, only for their hopes to be dashed. Nature sought advice from three scientists who have experienced the same disappointment.
A genetic screen that expresses single guide RNA libraries targeting host genes in the human cytomegalovirus genome enables identification of host factors and provides insights into their roles during the viral replication cycle.
ETS2—which is associated with inflammatory bowel disease, ankylosing spondylitis, primary sclerosing cholangitis and Takayasu’s arteritis—is a central regulator of human inflammatory macrophages.