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News and Views
Nature 461, 737-739 (8 October 2009) | doi:10.1038/461737a; Published online 7 October 2009
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Vision: Gene therapy in colour
Robert Shapley1
Abstract
Replacing a missing gene in adult colour-blind monkeys restores normal colour vision. How the new photoreceptor cells produced by this therapy lead to colour vision is a fascinating question.
Colour blindness is a common genetic disorder (affecting about 5–8% of males, although fewer than 1% of females) in which the absence of a single gene on the X chromosome leads to a specific loss of function. Normal human colour vision relies on three distinct photopigments in the retina's cone photoreceptors.
- Robert Shapley is at the Center for Neural Science, New York University, New York 10003, USA.
Email: shapley@cns.nyu.edu
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