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Nature 461, 177-178 (10 September 2009) | doi:10.1038/461177a; Published online 9 September 2009

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Sex determination: Birds do it with a Z gene

See associated Correspondence: Kuroiwa, Nature 462, 34 (November 2009)

Jennifer A. Marshall Graves1

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The gene that determines sex in birds has eluded scientists for a decade. Now this all-important locus is revealed as a gene on the Z chromosome known for its proclivity for determining sex in all kinds of animals.

Sex in birds, as well as in humans and other mammals, is determined by genes on specialized sex chromosomes. Mammalian females have two X chromosomes and males a single X and a degenerate Y chromosome that bears the male-dominant testis-determining gene SRY.

  1. Jennifer A. Marshall Graves is at the Research School of Biology, Australian National University, Canberra, ACT 2601, Australia.
    Email: jenny.graves@anu.edu.au

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