A regulatory protein thought to be crucial for maintaining the muscle stem-cell pool throughout life is shown to be dispensable in the adult. Muscle biologists are left wondering what fundamental things apply as time goes by.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Lepper, C., Conway, S. J. & Fan, C.-M. Nature 460, 627–631 (2009).
Montarras, D. & Buckingham, M. in Skeletal Muscle Repair and Regeneration (eds Schiaffano, S. & Partridge, T.) 19–44 (Springer, 2008).
Seale, P. et al. Cell 102, 777–786 (2000).
Oustanina, S., Hause, G. & Braun, T. EMBO J. 23, 3430–3439 (2004).
Relaix, F. et al. J. Cell Biol. 172, 91–102 (2006).
Péault, B. et al. Mol. Ther. 15, 867–877 (2007).
Sambasivan, R. et al. Dev. Cell 16, 810–821 (2009).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Partridge, T. Skeletal muscle comes of age. Nature 460, 584–585 (2009). https://doi.org/10.1038/460584a
Published:
Issue Date:
DOI: https://doi.org/10.1038/460584a