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Nature 460, 331-332 (16 July 2009) | doi:10.1038/460331a; Published online 8 July 2009

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Ageing: A midlife longevity drug?

Matt Kaeberlein1 & Brian K. Kennedy1

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The small molecule rapamycin, already approved for clinical use for various human disorders, has been found to significantly increase lifespan in mice. Is this a step towards an anti-ageing drug for people?

Anti-ageing drugs — compounds that slow the hands of time and allow humans to live far beyond their natural span — have long been fertile ground for science-fiction writers. More recently, however, the possibility that such compounds might exist, and might perhaps even be within reach, has gained scientific credibility.

  1. Matt Kaeberlein and Brian K. Kennedy are in the Departments of Pathology and Biochemistry, University of Washington, Seattle, Washington 98195, USA.
    Email: kaeber@u.washington.edu

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