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Nature 459, 917-918 (18 June 2009) | doi:10.1038/459917a; Published online 17 June 2009
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Organometallic chemistry: Charting the course of catalysis
Gregory L. Hamilton1 & F. Dean Toste1
Abstract
With palladium catalysts, chemists can manipulate ordinarily inert carbon–hydrogen bonds to build useful molecules from simple building blocks. How the catalysts guide this process has just become a bit clearer.
Carbon–hydrogen bonds are one of the most common types of linkage in organic molecules. But they do not react under most chemical conditions, and so are not generally considered to provide a useful handle for building complex molecules.
- Gregory L. Hamilton and F. Dean Toste are in the Department of Chemistry, University of California, Berkeley, California 94720–1460, USA.
Email: fdtoste@berkeley.edu
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