Access

News and Views

Nature 459, 336-337 (21 May 2009) | doi:10.1038/459336a; Published online 20 May 2009

Open Innovation Challenges

naturejobs

  • Director

    • The National Center for Complementary and Alternative Medicine (NCCAM)
    • Bethesda, MD

  • Faculty Positions

    • University of Texas Medical Branch
    • Galveston, TX United States
More science jobs
Post a job for free

Cancer: Melanoma troops massed

Paul H. Huang1 & Richard Marais1

Top

In many cancers, regulation of specific signalling molecules goes awry, affecting a host of other proteins and cellular processes. Proteomics is a useful systemic approach for identifying such extensive effects.

In most Western countries, the incidence of melanoma — a form of skin cancer linked to exposure to sunlight — doubles roughly every decade. Early removal of melanoma lesions leads to a good prognosis, but the outlook for patients with advanced melanoma is often bleak owing to a lack of effective treatments.

  1. Paul H. Huang and Richard Marais are at the Institute of Cancer Research, London SW3 6JB, UK.
    Email: richard.marais@icr.ac.uk

MORE ARTICLES LIKE THIS

These links to content published by NPG are automatically generated.

NEWS AND VIEWS

Stops along the RAS pathway in human genetic disease

Nature Medicine News and Views (01 Mar 2006)

RESEARCH

CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations

Oncogene Original Article

Phospho-ERK Staining Is a Poor Indicator of the Mutational Status of BRAF and NRAS in Human Melanoma

Journal of Investigative Dermatology Original Article

Mutually exclusive NRAS Q61R and BRAF V600E mutations at the single-cell level in the same human melanoma

Oncogene Original Article

See all 34 matches for Research