Table of contents
Volume 458 Number 7236 pp259-376
(this content only available online) indicates content that is available online only
Editorials
Turkey censors evolution p259
Turkey's government has done more for science than many. A row over a censored magazine and a sacked editor could put the good work at risk.
doi:10.1038/458259a
Health highway p259
President Obama's funds for electronic health records should prompt research — and controversy.
doi:10.1038/458259b
Filling the void p260
As science journalism declines, scientists must rise up and reach out.
doi:10.1038/458260a
Research Highlights
Planetary science: Fiery fountains p262
doi:10.1038/458262a
Evolution: Painful pairing p262
doi:10.1038/458262b
Chemistry: Buckyball expansion p262
doi:10.1038/458262c
Cancer therapeutics: Socking it to melanoma p262
doi:10.1038/458262d
Genomics: Staying in shape p262
doi:10.1038/458262e
Sexual selection: Cheap flights p262
doi:10.1038/458262f
Genomics: Big is beautiful p263
doi:10.1038/458263a
Molecular imaging: Nailing the molecule p263
doi:10.1038/458263b
Evolution: Fishy fangs p263
doi:10.1038/458263c
Materials: Five-star ice p263
doi:10.1038/458263d
Correction p263
doi:10.1038/458263e
News
Europe's green billions p264
Clean-energy investments target eastern Europe, but it remains to be seen whether they will create as many new jobs as hoped.
Quirin Schiermeier
doi:10.1038/458264a
Society sues journal over right to reply p264
Row between Max Planck Society and Wiley escalates.
Alison Abbott
doi:10.1038/458264b
Scientists in bone battle p265
Native Americans lay claim to 10,000-year-old skeletons.
Rex Dalton
doi:10.1038/458265a
America's long hard road to climate-change law p266
What challenges lie ahead as the United States tries to construct a working system for greenhouse-gas regulation? Jeff Tollefson reports.
Jeff Tollefson
doi:10.1038/458266a
Big interest in heavy drugs p269
The drug industry is seeking profits by modifying hydrogen in existing medications.
Katharine Sanderson
doi:10.1038/458269a
Roche vows to keep Genentech culture p270
It will be business as usual despite merger, say bosses.
Erika Check Hayden
doi:10.1038/458270a
Incoming chief to tackle woes of US food and drug agency p271
Obama nominates Margaret 'Peggy' Hamburg as FDA chief.
Meredith Wadman
doi:10.1038/458271a
Yale climate-change institute launched p272
doi:10.1038/458272a
NIH research to become permanently open access p272
doi:10.1038/458272b
Maths mistake blamed for killing off 'clean coal' plant p272
doi:10.1038/458272c
Soundbites from Copenhagen p272
Views from the International Scientific Congress on Climate Change, 10–12 March.
doi:10.1038/458272d
Lighter Higgs boson harder to find p273
doi:10.1038/458273a
Hospital investigation reveals long-running fraud p273
doi:10.1038/458273b
News Features
Science journalism: Supplanting the old media? p274
Science journalism is in decline; science blogging is growing fast. But can the one replace the other, asks Geoff Brumfiel.
doi:10.1038/458274a
Clinical epidemiology: Archived answers p278
The switch to electronic medical records opens up a potential wealth of data for researchers, if major obstacles can be overcome, reports Katharine Gammon.
doi:10.1038/458278a
Correspondence
Diversity of funding sources and topics is key to survival p281
Brian Derby
doi:10.1038/458281a
Grant-writing offices would let scientists get on with research p281
Cecile Perrault
doi:10.1038/458281b
We need more insight into what's worth paying for p281
William Gunn
doi:10.1038/458281c
Backlogged system in Australia shuts out new investigators p281
Darren Saunders
doi:10.1038/458281d
Essay
Do nations go to war over water? p282
Wendy Barnaby was asked to write a book about water wars — then the facts got in the way of her story.
Wendy Barnaby
doi:10.1038/458282a
Books and Arts
When wise words are not enough p284
Thomas Homer-Dixon argues that opinion-makers must demonstrate a better grasp of how societies rise and fall if they are to steer nations successfully through many of this century's major crises.
Thomas Homer-Dixon
doi:10.1038/458284a
Universe in a box p285
Pedro Ferreira reviews Joseph Cornell and Astronomy: A Case for the Stars by Kirsten Hoving
doi:10.1038/458285a
A romp through science fiction p286
Stefano Tonzani reviews Nanovision: Engineering the Future by Colin Milburn
doi:10.1038/458286a
Disturbing the Arkansas river p287
Laura Spinney reviews Over The River, A Work in Progress
doi:10.1038/458287a
Not one to watch p287
Michael White reviews Watchmen
doi:10.1038/458287b
News and Views
Spectroscopy: Handedness in quick time p289
The handedness of chiral molecules can be probed spectroscopically, but acquiring data can take hours, which is a problem for time-resolved studies. The latest method records such data in a flash.
Patrick H. Vaccaro
doi:10.1038/458289a
See also: Editor's summary
Cancer: The nuances of therapy p290
Oncologists use drugs that limit a tumour's blood supply to prevent its growth. Although the initial effects of these drugs are beneficial to patients, new data suggest that their long-term effects warrant further study.
Lee M. Ellis & David A. Reardon
doi:10.1038/458290a
50 & 100 years ago p291
doi:10.1038/458291a
Geophysics: Hot blanket in Earth's deep crust p292
Studies of rocks from Earth's crust suggest that the lower crust is a good thermal insulator. The knock-on effects of this finding are many — one being the crust's increased potential to generate more magma.
Jean Braun
doi:10.1038/458292a
See also: Editor's summary
Dinosaurs: Fuzzy origins for feathers p293
Cretaceous fossil deposits in China are famous for their feathered dinosaurs. But the surprising discovery of a herbivorous dinosaur with a filamentous coat raises fresh questions about the evolution of feathers.
Lawrence M. Witmer
doi:10.1038/458293a
See also: Editor's summary
Chemistry: Thinking outside the flask p294
Stephen Davey
doi:10.1038/458294a
Global change: West-side story of Antarctic ice p295
During the past five million years, the West Antarctic ice sheet has waxed and waned in size. A two-pronged reconstruction of that history provides clues to the ice sheet's future behaviour.
Philippe Huybrechts
doi:10.1038/458295a
See also: Editor's summary
Neuroscience: Secret of synapse specificity p296
How does the brain organize all of the information stored in memory? On the basis of a state-of-the-art imaging study of neuronal activity in real time, the answer seems to be, through specificity in space and time.
Scott M. Thompson & Hayley A. Mattison
doi:10.1038/458296a
See also: Editor's summary
Brief Communications Arising
Hippopotamus and whale phylogeny pE1
Jonathan H. Geisler & Jessica M. Theodor
doi:10.1038/nature07776
First paragraph | Full Text | PDF (346K)
Thewissen et al. reply pE5
J. G. M. Thewissen, Lisa Noelle Cooper, Mark T. Clementz, Sunil Bajpai & B. N. Tiwari
doi:10.1038/nature07775
First paragraph | Full Text | PDF (346K)
Articles
Activation of CaMKII in single dendritic spines during long-term potentiation p299
Seok-Jin R. Lee, Yasmin Escobedo-Lozoya, Erzsebet M. Szatmari & Ryohei Yasuda
doi:10.1038/nature07842
Abstract | Full Text | PDF (896K) | Supplementary information
See also: Editor's summary | News and Views by Thompson & Mattison
Design and engineering of an O2 transport protein p305
Ronald L. Koder, J. L. Ross Anderson, Lee A. Solomon, Konda S. Reddy, Christopher C. Moser & P. Leslie Dutton
doi:10.1038/nature07841
Abstract | Full Text | PDF (1,178K) | Supplementary information
See also: Editor's summary
Letters
Femtosecond characterization of vibrational optical activity of chiral molecules p310
Hanju Rhee, Young-Gun June, Jang-Soo Lee, Kyung-Koo Lee, Jeong-Hyon Ha, Zee Hwan Kim, Seung-Joon Jeon & Minhaeng Cho
doi:10.1038/nature07846
First paragraph | Full Text | PDF (1,099K) | Supplementary information
See also: Editor's summary | News and Views by Vaccaro
Hybrid organic–inorganic rotaxanes and molecular shuttles p314
Chin-Fa Lee, David A. Leigh, Robin G. Pritchard, David Schultz, Simon J. Teat, Grigore A. Timco & Richard E. P. Winpenny
doi:10.1038/nature07847
First paragraph | Full Text | PDF (969K) | Supplementary information
See also: Editor's summary
Temperature-dependent thermal diffusivity of the Earth's crust and implications for magmatism p319
Alan G. Whittington, Anne M. Hofmeister & Peter I. Nabelek
doi:10.1038/nature07818
First paragraph | Full Text | PDF (413K) | Supplementary information
See also: Editor's summary | News and Views by Braun
Obliquity-paced Pliocene West Antarctic ice sheet oscillations p322
T. Naish, R. Powell, R. Levy, G. Wilson, R. Scherer, F. Talarico, L. Krissek, F. Niessen, M. Pompilio, T. Wilson, L. Carter, R. DeConto, P. Huybers, R. McKay, D. Pollard, J. Ross, D. Winter, P. Barrett, G. Browne, R. Cody, E. Cowan, J. Crampton, G. Dunbar, N. Dunbar, F. Florindo, C. Gebhardt, I. Graham, M. Hannah, D. Hansaraj, D. Harwood, D. Helling, S. Henrys, L. Hinnov, G. Kuhn, P. Kyle, A. Läufer, P. Maffioli, D. Magens, K. Mandernack, W. McIntosh, C. Millan, R. Morin, C. Ohneiser, T. Paulsen, D. Persico, I. Raine, J. Reed, C. Riesselman, L. Sagnotti, D. Schmitt, C. Sjunneskog, P. Strong, M. Taviani, S. Vogel, T. Wilch & T. Williams
doi:10.1038/nature07867
First paragraph | Full Text | PDF (1,456K) | Supplementary information
See also: Editor's summary | News and Views by Huybrechts
Modelling West Antarctic ice sheet growth and collapse through the past five million years p329
David Pollard & Robert M. DeConto
doi:10.1038/nature07809
First paragraph | Full Text | PDF (1,246K) | Supplementary information
See also: Editor's summary | News and Views by Huybrechts
An Early Cretaceous heterodontosaurid dinosaur with filamentous integumentary structures p333
Xiao-Ting Zheng, Hai-Lu You, Xing Xu & Zhi-Ming Dong
doi:10.1038/nature07856
First paragraph | Full Text | PDF (1,066K) | Supplementary information
See also: Editor's summary | News and Views by Witmer
Population genomics of domestic and wild yeasts p337
Gianni Liti, David M. Carter, Alan M. Moses, Jonas Warringer, Leopold Parts, Stephen A. James, Robert P. Davey, Ian N. Roberts, Austin Burt, Vassiliki Koufopanou, Isheng J. Tsai, Casey M. Bergman, Douda Bensasson, Michael J. T. O'Kelly, Alexander van Oudenaarden, David B. H. Barton, Elizabeth Bailes, Alex N. Nguyen, Matthew Jones, Michael A. Quail, Ian Goodhead, Sarah Sims, Frances Smith, Anders Blomberg, Richard Durbin & Edward J. Louis
doi:10.1038/nature07743
First paragraph | Full Text | PDF (490K) | Supplementary information
See also: Editor's summary
Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae p342
Joseph Schacherer, Joshua A. Shapiro, Douglas M. Ruderfer & Leonid Kruglyak
doi:10.1038/nature07670
First paragraph | Full Text | PDF (338K) | Supplementary information
See also: Editor's summary
Antiviral immunity in Drosophila requires systemic RNA interference spread p346
Maria-Carla Saleh, Michel Tassetto, Ronald P. van Rij, Bertsy Goic, Valérie Gausson, Bassam Berry, Caroline Jacquier, Christophe Antoniewski & Raul Andino
doi:10.1038/nature07712
First paragraph | Full Text | PDF (700K) | Supplementary information
See also: Editor's summary
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses p351
Ye Zheng, Ashutosh Chaudhry, Arnold Kas, Paul deRoos, Jeong M. Kim, Tin-Tin Chu, Lynn Corcoran, Piper Treuting, Ulf Klein & Alexander Y. Rudensky
doi:10.1038/nature07674
First paragraph | Full Text | PDF (1,046K) | Supplementary information
See also: Editor's summary
Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells p357
Satohiro Okuda, Hiroki Tsutsui, Keiko Shiina, Stefanie Sprunck, Hidenori Takeuchi, Ryoko Yui, Ryushiro D. Kasahara, Yuki Hamamura, Akane Mizukami, Daichi Susaki, Nao Kawano, Takashi Sakakibara, Shoko Namiki, Kie Itoh, Kurataka Otsuka, Motomichi Matsuzaki, Hisayoshi Nozaki, Tsuneyoshi Kuroiwa, Akihiko Nakano, Masahiro M. Kanaoka, Thomas Dresselhaus, Narie Sasaki & Tetsuya Higashiyama
doi:10.1038/nature07882
First paragraph | Full Text | PDF (640K) | Supplementary information
See also: Editor's summary
The DNA-encoded nucleosome organization of a eukaryotic genome p362
Noam Kaplan, Irene K. Moore, Yvonne Fondufe-Mittendorf, Andrea J. Gossett, Desiree Tillo, Yair Field, Emily M. LeProust, Timothy R. Hughes, Jason D. Lieb, Jonathan Widom & Eran Segal
doi:10.1038/nature07667
First paragraph | Full Text | PDF (578K) | Supplementary information
See also: Editor's summary
Transmembrane passage of hydrophobic compounds through a protein channel wall p367
Elizabeth M. Hearn, Dimki R. Patel, Bryan W. Lepore, Mridhu Indic & Bert van den Berg
doi:10.1038/nature07678
First paragraph | Full Text | PDF (643K) | Supplementary information
See also: Editor's summary
Naturejobs
ProspectsStem cell recruits p371
Lifting the stem-cell ban has repercussions that go beyond science ethics and disease cures.
Gene Russo
doi:10.1038/nj7236-371a
Special Report
Personnel dilemma p372
The hiring of US science faculty members has slowed considerably. Karen Kaplan tracks the administrators who are trying to keep programmes intact.
Karen Kaplan
doi:10.1038/nj7236-372a
Career View
Louise Ryan, chief, mathematical and information sciences, Commonwealth Scientific and Industrial Research Organisation, Sydney, Australia p374
Biostatistician seeks to boost statistics research posts in Australia.
Virginia Gewin
doi:10.1038/nj7236-374a
A bill to care for carers p374
Congresswoman seeks legislation to provide grant extensions for federally funded scientists who need extended family leave.
Heidi Ledford
doi:10.1038/nj7236-374b
As simple as possible p374
Is my marketability more important than my curiosity?
Sam Walcott
doi:10.1038/nj7236-374c
