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Nature 457, 1079 (26 February 2009) | doi:10.1038/4571079b; Published online 25 February 2009

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Rare BSE mutation raises concerns over risks to public health

Malcolm A. Ferguson-Smith1 & Jürgen A. Richt2

  1. Cambridge University Department of Veterinary Medicine, Madingley Road, Cambridge CB3 0ES, UK
    Email: maf12@cam.ac.uk
  2. College of Veterinary Medicine, Kansas State University, K224B Mosier Hall, Manhattan, Kansas 66506-5601, USA

Atypical forms (known as H- and L-type) of bovine spongiform encephalopathy (BSE) have recently appeared in several European countries as well as in Japan, Canada and the United States. This raises the unwelcome possibility that variant Creutzfeldt–Jakob disease (vCJD) could increase in the human population.

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