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Nature 456, 333-334 (20 November 2008) | doi:10.1038/456333a; Published online 19 November 2008
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Postdoctoral Research Fellow ? Andy Chan?s Lab / Immunology
- Genentech
- South San Francisco, CA, USA
Director of Bioinformatics
- University of the Witwatersrand, Johannesburg
- Johannesburg, South Africa
Cell biology: Nuclear order out of chaos
Tom Misteli1
Abstract
How cells build their internal structures remains one of the central mysteries in cell biology. If the cell nucleus is anything to go by, stochastic assembly and self-organization seem to be key.
As anyone knows who has ever put together one of those home-assembly bookshelves, most man-made structures can only be built by following a defined sequence of steps. It is difficult to set aside this preconceived notion of linear assembly when thinking about how cellular structures emerge.
- Tom Misteli is at the National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Email: mistelit@mail.nih.gov
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