Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 455, 879-880 (16 October 2008) | doi:10.1038/455879a; Published online 15 October 2008
Open Innovation Challenges
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
- More Challenges
- Powered by:
nature jobs
Manager Medical Writitng
- Indegene Lifesystems Pvt. Ltd
- Bengaluru 560 071 India
Postdoctoral Associate in Enzyme Biochemistry
- Cornell University
- Ithaca, New York
Structural biology: Clamour for a kiss
Anastassios Economou1
Abstract
Precisely how proteins snake their way through channels in cell membranes is unclear. Complexes between the SecY channel and its motor protein, and the use of a 'molecular endoscope', provide fascinating clues.
To cross cellular membranes, secretory proteins use specialized channels such as that known as SecY. When ribosomes start synthesizing secretory proteins, the ribosome–protein complex is hijacked to the mouth of SecY.
- Anastassios Economou is at the Institute of Molecular Biology and Biotechnology, Foundation of Research and Technology-Hellas, and in the Department of Biology, University of Crete, PO Box 1385, Iraklio, Crete, Greece.
Email: aeconomo@imbb.forth.gr
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Cross-talk between catalytic and regulatory elements in a DEAD motor domain is essential for SecA functionThe EMBO Journal Article (01 Mar 2001)
Structure of a complex of the ATPase SecA and the protein-translocation channelNature Article (16 Oct 2008)
Preprotein-controlled catalysis in the helicase motor of SecAThe EMBO Journal Article (20 Jun 2007)
See all 5 matches for Research