Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 455, 745-747 (9 October 2008) | doi:10.1038/455745a; Published online 8 October 2008
Open Innovation Challenges
-
Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
-
Efficient Chromosome Doubling: Plant Cell Division
The Seeker is looking for an efficient chromosome doubling method in plants and in particular, metho...
- More Challenges
- Powered by:
nature jobs
Gastroenterologist
- Florida Gastroenterology Practice
- Florida, USA
Director of NMR
- New York Structural Biology Center
- New York, New York
Immunology: Helpful T cells are sticky
Elissa K. Deenick1 & Stuart G. Tangye1
Abstract
Prolonged physical interaction between helper T cells and antibody-producing B cells is crucial for efficient immune responses. Mutations in a protein that underlies this process cause human disease.
The production of antibodies by B cells is essential for protective immunity following vaccination or exposure to infectious pathogens. The development of antibody-secreting B cells occurs in discrete areas of lymphoid tissues called germinal centres1, 2, the formation of which depends on interactions between B cells and T cells bearing the CD4 molecule on their surface (CD4+ T cells).
- Elissa K. Deenick and Stuart G. Tangye are at the Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, 2010 New South Wales, Australia.
Email: e.deenick@garvan.org.au
Email: s.tangye@garvan.org.au
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
B cell memory: Sapping the T cellNature Medicine News and Views (01 Feb 2003)
The need for natural killer T cellsNature Medicine News and Views (01 Mar 2005)
See all 7 matches for News And ViewsRESEARCH
A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteinsNature Immunology Article (01 Jun 2001)
Rate of Protein Biosynthesis in Hepatoma 223Nature Letters to Editor (22 Jan 1966)
See all 15 matches for Research