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Commentary

Nature 455, 730-731 (9 October 2008) | doi:10.1038/455730a; Published online 8 October 2008

Open Innovation Challenges

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A network solution

Adriano Henney1 & Giulio Superti-Furga2

  1. Adriano Henney is a director of Global Discovery Enabling Capabilities and Sciences at AstraZeneca, Alderley Park, UK.
    Email: adriano.henney@btinternet.com
  2. Giulio Superti-Furga directs the Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, Austria.
    Email: gsuperti@cemm.oeaw.ac.at

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With the right plan, systems biology can empower drug discovery, say Adriano Henney and Giulio Superti-Furga. Field leaders have contributed and now the authors want to hear from you.

Systems biology focuses on interactions within and between the mechanisms that combine to give rise to the function and behaviour of a biological system. To some it is the logical and inevitable next-level understanding that will propel drug discovery from empiricism to mechanism-based rational design.