FIGURE 1. Synteny maps showing the comparative organization of Plasmodium chromosomes.
From the following article:
Comparative genomics of the neglected human malaria parasite Plasmodium vivax
Jane M. Carlton, John H. Adams, Joana C. Silva, Shelby L. Bidwell, Hernan Lorenzi, Elisabet Caler, Jonathan Crabtree, Samuel V. Angiuoli, Emilio F. Merino, Paolo Amedeo, Qin Cheng, Richard M. R. Coulson, Brendan S. Crabb, Hernando A. del Portillo, Kobby Essien, Tamara V. Feldblyum, Carmen Fernandez-Becerra, Paul R. Gilson, Amy H. Gueye, Xiang Guo, Simon Kang'a, Taco W. A. Kooij, Michael Korsinczky, Esmeralda V.-S. Meyer, Vish Nene, Ian Paulsen, Owen White, Stuart A. Ralph, Qinghu Ren, Tobias J. Sargeant, Steven L. Salzberg, Christian J. Stoeckert, Steven A. Sullivan, Marcio M. Yamamoto, Stephen L. Hoffman, Jennifer R. Wortman, Malcolm J. Gardner, Mary R. Galinski, John W. Barnwell & Claire M. Fraser-Liggett
Nature 455, 757-763(9 October 2008)
doi:10.1038/nature07327

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Putative orthologues were computed between P. falciparum (Pf), P. vivax (Pv), P. knowlesi (Pk) and P. y. yoelii (Py) proteomes and used to define blocks of synteny (shaded regions) between Py–Pk, Pv–Pk and Pv–Pf chromosomes. Genes on contigs that could not be assigned to chromosomes are not shown (see Supplementary Information). The composite rodent malaria parasite (cRMP) chromosomes generated in ref 18 are shown. Plots below the Pv chromosomes display the following: MS, the position of polymorphic microsatellites; (G+C)-skew, the base composition ((G-C)/(G+C)) within each strand in a 5-kb window; G+C, the percentage of bases in a 2-kb window that are G and C (%). Tracks within the Pv–Pk bracket show two evolutionary parameters: dS (number of synonymous substitutions per synonymous site; top) and
(ratio of dN (non-synonymous substitutions per non-synonymous site) to dS; bottom). Horizontal red lines on the G+C (%), dS and
tracks indicate the average value for that chromosome. a–d, Distribution of selective constraints (
) for the gene ontology classifications biological process (a), molecular function (b) and cellular component (c). Selective constraint is also shown for several motifs (d): proteins containing predicted transmembrane domains (TM) and/or signal peptides (SP); GPI-anchored proteins; and proteins predicted to be exported (exportome). Each grey box represents the interquartile range, which contains the sample's 25% to 75% range (quartiles Q1 to Q3, respectively), and the median is indicated (black horizontal bar within the interquartile range). Horizontal tick marks outside of the interquartile range show the range of all elements within Q1 - 1.5
interquartile range and Q3 + 1.5
interquartile range (
99.3% interval of a normal distribution).
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