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News and Views
Nature 455, 604-605 (2 October 2008) | doi:10.1038/455604a; Published online 1 October 2008
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Animal Science Technician
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- Cincinnati, OH, USA
Researchers
- AIRC
- Milan, Italy
Regenerative medicine: Short cut to cell replacement
Robert Blelloch1
Abstract
To make one differentiated cell type from another, a 'stopover' at an undifferentiated state is often required. An alternative method offering an efficient direct route could have implications for disease treatment.
Regenerative medicine aims to repair diseased or damaged tissues by replacing the affected cells with healthy, functional cells of the same type. The prospects of this discipline have been boosted by the promise of embryonic stem (ES) cells, which are pluripotent — that is, they can differentiate into any cell type — and which can be maintained in culture to 'self-renew' indefinitely.
- Robert Blelloch is at the Institute for Regeneration Medicine, Center for Reproductive Sciences, and Department of Urology, University of California, San Francisco, San Francisco, California 94143–0525, USA.
Email: blellochr@stemcell.ucsf.edu
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