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Nature 455, 481-483 (25 September 2008) | doi:10.1038/455481a; Published online 24 September 2008
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Microbiology: Metagenomics
Philip Hugenholtz1 & Gene W. Tyson2
Abstract
Ten years after the term metagenomics was coined, the approach continues to gather momentum. This culture-independent, molecular way of analysing environmental samples of cohabiting microbial populations has opened up fresh perspectives on microbiology.
Why the 'meta' in metagenomics?Genomics determines the complete genetic complement of an organism by high-throughput sequencing of the base pairs of its DNA.
- Philip Hugenholtz is in the Microbial Ecology Program, DOE Joint Genome Institute, Walnut Creek, California 94598, USA.
Email: phugenholtz@lbl.gov - Gene W. Tyson is in the Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Email: gtyson@mit.edu
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