Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 455, 178-179 (11 September 2008) | doi:10.1038/455178a; Published online 10 September 2008
Open Innovation Challenges
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
- More Challenges
- Powered by:
nature jobs
Tier II Canada Research Chair in Cellular Science and Human Health
- Concordia University
- Montreal, Quebec Canada
Head-Preclinical
- Syngene International
- Bangalore, Karnataka 560099 India
Schizophrenia: Incriminating genomic evidence
James R. Lupski1
Abstract
The genetic factors that contribute to schizophrenia can vary, making it difficult to pinpoint which DNA changes are the main culprits. Large genome-wide studies provide the most reliable clues yet.
Schizophrenia is a chronic, debilitating illness with both neurological and psychiatric features, and it affects an estimated 1% of the world's population. Intense research into this disorder clearly points to the involvement of a significant genetic component, but genetic studies of schizophrenia have generally been disappointing as the data obtained often cannot be reproduced1.
- James R. Lupski is in the Departments of Molecular and Human Genetics, and of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, Texas 77030, USA.
Email: jlupski@bcm.tmc.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Psychiatric genetics gets a boostNature Genetics News and Views (01 Sep 2008)
Neuropsychiatric disorders Shared genetics of bipolar disorder and schizophreniaNature Reviews Neurology News and Views (01 Jun 2009)
See all 4 matches for News And ViewsRESEARCH
Temporal changes in allele frequency, genetic variation and inbreeding depression in small populations of the guppy, Poecilia reticulataHeredity Original Article
Rare chromosomal deletions and duplications increase risk of schizophreniaNature Letters to Editor (11 Sep 2008)
See all 30 matches for Research