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Editorials

Turning blight into bloom p137

As we become an ever more urban species, cities will be a crucial front in the fight against climate change. Scientists, architects and planners must join forces to make our metropolitan future clean and sustainable.

doi:10.1038/455137a


Brave new worlds p137

A new series of essays looks back at scientific meetings that had world-changing consequences.

doi:10.1038/455137b

See also: Editor's summary


A bigger picture p138

Beneath cancer's daunting complexity lies a simplicity that gives grounds for hope.

doi:10.1038/455138a


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Research Highlights

Neuroeconomics: Subliminal choices p140

doi:10.1038/455140a


Climate change: 'Hockey stick' holds up p140

doi:10.1038/455140b


Sexual imprinting: Facing Oedipus p140

doi:10.1038/455140c


X-ray physics: Superman's sharper vision p140

doi:10.1038/455140d


Immunology: Holistic medicine p140

doi:10.1038/455140e


Organic chemistry: Tag-team catalysts p140

doi:10.1038/455140f


Genetics: Sweet longevity p141

doi:10.1038/455141a


Molecular immunology: Friendly antibodies p141

doi:10.1038/455141b


Glaciology: Judge a basin by its cover p141

doi:10.1038/455141c


Astrophysics: Cloudy skies p141

doi:10.1038/455141d


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Journal Club

Journal club p141

Michael K. Richardson

doi:10.1038/455141e


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News

China rushes through major funding system p142

Medical researchers hurry to hit deadline for megaproject cash.

David Cyranoski

doi:10.1038/455142a


Megacity project seeks to gauge urban pollution p142

Europe's air quality comes under scrutiny.

Declan Butler

doi:10.1038/455142b


Lab politics p143

In the second of our election-themed podcasts available online, Nature looks at where US biomedical research might head after November's presidential election.

doi:10.1038/455143a


Change at the top for climate panel p144

Rajendra Pachauri keeps post, but working groups gain fresh leadership.

Jeff Tollefson

doi:10.1038/455144a


French university under fire for culling macaques p145

Death of research monkeys slammed as morally wrong.

Alison Abbott

doi:10.1038/455145a


'Lucky' Louisiana unprepared for Gustav p147

Coastal restoration hit by hurricane.

Emma Marris

doi:10.1038/455147a


Cancer complexity slows quest for cure p148

Genomic analysis reveals multiple mutations in tumours.

Erika Check Hayden

doi:10.1038/455148a


Genomics institute secures its future p149

$400-million endowment edges Broad Institute towards independence.

Heidi Ledford

doi:10.1038/455149a


Physicist convicted over links with Iran and China p150

doi:10.1038/455150a


Lancet retracts paper on stem-cell treatment p150

doi:10.1038/455150b


India wins waiver to buy nuclear technology p150

doi:10.1038/455150c


China pauses on turning coal into liquid fuel p151

doi:10.1038/455151a


Wellcome Trust goes into partnership with India p151

doi:10.1038/455151b


Fears for fading fireflies prompt online monitor p151

doi:10.1038/455151c


Correction p151

doi:10.1038/455151d


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News Features

Palaeontology: The new mother lode p153

Palaeontologists in Argentina are exploring a trove of fossils that is rewriting evolutionary history. Rex Dalton reports.

doi:10.1038/455153a


Particle physics: The race to break the standard model p156

The Large Hadron Collider is the latest attempt to move fundamental physics past the frustratingly successful 'standard model'. But it is not the only way to do it. Geoff Brumfiel surveys the contenders attempting to capture the prize before the collider gets up to speed.

doi:10.1038/455156a


Protein engineering: The fate of fingers p160

Proteins with 'zinc fingers' designed to bind almost any DNA sequence will soon be available to any lab that wants them — from two very different sources. Helen Pearson reports on a revolution in designer biology.

doi:10.1038/455160a


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Correspondence

Doping: a paradigm shift has taken place in testing p166

Pierre-Edouard Sottas, Christophe Saudan & Martial Saugy

doi:10.1038/455166a


Doping: probability that testing doesn't tell us anything new p166

Geoffrey Baird

doi:10.1038/455166b


Doping: ignorance of basic statistics is all too common p166

Matthew Fero

doi:10.1038/455166c


Doping: similar problems arise in medical clinics p167

Eric L. Altschuler

doi:10.1038/455167a


Playing the system to give low-impact journal more clout p167

Tomás caron Opatrný

doi:10.1038/455167b


Changing the rules won't stop the rise of a new superpower p167

Robbert Maseland

doi:10.1038/455167c


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Books and Arts

There's no place like home? p168

A bold attempt to synthesize the effects of geography on the world's population through maps highlights some interesting paradoxes, explains Yi-Fu Tuan.

Yi-Fu Tuan reviews The Power of Place: Geography, Destiny, and Globalization's Rough Landscape by Harm de Blij

doi:10.1038/455168a

See also: Editor's summary


A toolbox for policy planners p169

Robert Lempert reviews The Handbook of Technology Foresight

doi:10.1038/455169a


Potatoes and poverty p170

Sandra Knapp reviews Propitious Esculent: The Potato in World History by John Reader

doi:10.1038/455170a


Building from the environment p171

Colin Martin reviews Abundant Australia

doi:10.1038/455171a


Hidden treasures: the moulage museum in Zurich p172

Medical students still learn about skin diseases from hundreds of wax models that also record early cancer research and the ravages of syphilis, reports Alison Abbott.

Alison Abbott

doi:10.1038/455172a


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Essay

Meetings that changed the world: Paris 1951: The birth of CERN p174

François de Rose chaired the meeting that founded Europe's premier facility for experimental nuclear and particle research. Here he relives the five days of drama that changed the world of physics.

François de Rose

doi:10.1038/455174a

See also: Editor's summary


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News and Views

Plant biology: Hormones branch out p176

Evidence points to the existence of a hitherto uncharacterized type of hormone that controls different aspects of plant growth and interaction. The hunt for that hormone is heating up.

Harry Klee

doi:10.1038/455176a

See also: Editor's summary


Gamma-ray bursts: Light on the distant Universe p177

Observations of a long-lasting gamma-ray burst, one that has the brightest optical counterpart yet discovered, challenge theoretical understanding of these bursts but may enhance their usefulness as cosmic probes.

Jonathan Grindlay

doi:10.1038/455177a

See also: Editor's summary


Schizophrenia: Incriminating genomic evidence p178

The genetic factors that contribute to schizophrenia can vary, making it difficult to pinpoint which DNA changes are the main culprits. Large genome-wide studies provide the most reliable clues yet.

James R. Lupski

doi:10.1038/455178a

See also: Editor's summary


50 & 100 Years Ago p179

doi:10.1038/455179a


Quantum mechanics: Entangled families p180

Quantum entanglement comes in a rich variety of types and families if more than two particles are involved. Experiments with photons are opening up fresh ways to systematically study multi-particle entanglement.

Markus Aspelmeyer & Jens Eisert

doi:10.1038/455180a


Biomolecular engineering: Negative success in tiny tree p181

Christopher Surridge

doi:10.1038/455181a

See also: Editor's summary


Correction p181

doi:10.1038/455181b


Obituary: Neil Bartlett (1932–2008) p182

Founder of noble-gas chemistry.

Karl O. Christe

doi:10.1038/455182a


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Brief Communications Arising

Arctic tropospheric warming amplification? pE1

Peter W. Thorne

doi:10.1038/nature07256


Recent Arctic warming vertical structure contested pE2

A. N. Grant, S. Brönnimann & L. Haimberger

doi:10.1038/nature07257


Arctic warming aloft is data set dependent pE3

Cecilia M. Bitz & Qiang Fu

doi:10.1038/nature07258


Graversen et al. reply pE4

R. G. Graversen, T. Mauritsen, M. Tjernström, E. Källén & G. Svensson

doi:10.1038/nature07259


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Articles

Broadband observations of the naked-eye bold gamma-ray burst GRB 080319B p183

J. L. Racusin, S. V. Karpov, M. Sokolowski, J. Granot, X. F. Wu, V. Pal'shin, S. Covino, A. J. van der Horst, S. R. Oates, P. Schady, R. J. Smith, J. Cummings, R. L. C. Starling, L. W. Piotrowski, B. Zhang, P. A. Evans, S. T. Holland, K. Malek, M. T. Page, L. Vetere, R. Margutti, C. Guidorzi, A. P. Kamble, P. A. Curran, A. Beardmore, C. Kouveliotou, L. Mankiewicz, A. Melandri, P. T. O'Brien, K. L. Page, T. Piran, N. R. Tanvir, G. Wrochna, R. L. Aptekar, S. Barthelmy, C. Bartolini, G. M. Beskin, S. Bondar, M. Bremer, S. Campana, A. Castro-Tirado, A. Cucchiara, M. Cwiok, P. D'Avanzo, V. D'Elia, M. Della Valle, A. de Ugarte Postigo, W. Dominik, A. Falcone, F. Fiore, D. B. Fox, D. D. Frederiks, A. S. Fruchter, D. Fugazza, M. A. Garrett, N. Gehrels, S. Golenetskii, A. Gomboc, J. Gorosabel, G. Greco, A. Guarnieri, S. Immler, M. Jelinek, G. Kasprowicz, V. La Parola, A. J. Levan, V. Mangano, E. P. Mazets, E. Molinari, A. Moretti, K. Nawrocki, P. P. Oleynik, J. P. Osborne, C. Pagani, S. B. Pandey, Z. Paragi, M. Perri, A. Piccioni, E. Ramirez-Ruiz, P. W. A. Roming, I. A. Steele, R. G. Strom, V. Testa, G. Tosti, M. V. Ulanov, K. Wiersema, R. A. M. J. Wijers, J. M. Winters, A. F. Zarnecki, F. Zerbi, P. Mészáros, G. Chincarini & D. N. Burrows

doi:10.1038/nature07270

See also: Editor's summary | News and Views by Grindlay


Strigolactone inhibition of shoot branching p189

Victoria Gomez-Roldan, Soraya Fermas, Philip B. Brewer, Virginie Puech-Pagès, Elizabeth A. Dun, Jean-Paul Pillot, Fabien Letisse, Radoslava Matusova, Saida Danoun, Jean-Charles Portais, Harro Bouwmeester, Guillaume Bécard, Christine A. Beveridge, Catherine Rameau & Soizic F. Rochange

doi:10.1038/nature07271

See also: Editor's summary | News and Views by Klee


Inhibition of shoot branching by new terpenoid plant hormones p195

Mikihisa Umehara, Atsushi Hanada, Satoko Yoshida, Kohki Akiyama, Tomotsugu Arite, Noriko Takeda-Kamiya, Hiroshi Magome, Yuji Kamiya, Ken Shirasu, Koichi Yoneyama, Junko Kyozuka & Shinjiro Yamaguchi

doi:10.1038/nature07272

See also: Editor's summary | News and Views by Klee


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Letters

A blast wave from the 1843 eruption of eta Carinae p201

Nathan Smith

doi:10.1038/nature07269

See also: Editor's summary


A Mott insulator of fermionic atoms in an optical lattice p204

Robert Jördens, Niels Strohmaier, Kenneth Günter, Henning Moritz & Tilman Esslinger

doi:10.1038/nature07244

See also: Editor's summary


The transpiration of water at negative pressures in a synthetic tree p208

Tobias D. Wheeler & Abraham D. Stroock

doi:10.1038/nature07226

See also: Editor's summary


Old-growth forests as global carbon sinks p213

Sebastiaan Luyssaert, E. -Detlef Schulze, Annett Börner, Alexander Knohl, Dominik Hessenmöller, Beverly E. Law, Philippe Ciais & John Grace

doi:10.1038/nature07276

See also: Editor's summary


Upward migration of Vesuvius magma chamber over the past 20,000 years p216

B. Scaillet, M. Pichavant & R. Cioni

doi:10.1038/nature07232

See also: Editor's summary


Understanding the limits to generalizability of experimental evolutionary models p220

Samantha E. Forde, Robert E. Beardmore, Ivana Gudelj, Sinan S. Arkin, John N. Thompson & Laurence D. Hurst

doi:10.1038/nature07152

See also: Editor's summary


High bacterivory by the smallest phytoplankton in the North Atlantic Ocean p224

Mikhail V. Zubkov & Glen A. Tarran

doi:10.1038/nature07236

See also: Editor's summary


Neural correlates, computation and behavioural impact of decision confidence p227

Adam Kepecs, Naoshige Uchida, Hatim A. Zariwala & Zachary F. Mainen

doi:10.1038/nature07200

See also: Editor's summary


Large recurrent microdeletions associated with schizophrenia p232

Hreinn Stefansson, Dan Rujescu, Sven Cichon, Olli P. H. Pietiläinen, Andres Ingason, Stacy Steinberg, Ragnheidur Fossdal, Engilbert Sigurdsson, Thordur Sigmundsson, Jacobine E. Buizer-Voskamp, Thomas Hansen, Klaus D. Jakobsen, Pierandrea Muglia, Clyde Francks, Paul M. Matthews, Arnaldur Gylfason, Bjarni V. Halldorsson, Daniel Gudbjartsson, Thorgeir E. Thorgeirsson, Asgeir Sigurdsson, Adalbjorg Jonasdottir, Aslaug Jonasdottir, Asgeir Bjornsson, Sigurborg Mattiasdottir, Thorarinn Blondal, Magnus Haraldsson, Brynja B. Magnusdottir, Ina Giegling, Hans-Jürgen Möller, Annette Hartmann, Kevin V. Shianna, Dongliang Ge, Anna C. Need, Caroline Crombie, Gillian Fraser, Nicholas Walker, Jouko Lonnqvist, Jaana Suvisaari, Annamarie Tuulio-Henriksson, Tiina Paunio, Timi Toulopoulou, Elvira Bramon, Marta Di Forti, Robin Murray, Mirella Ruggeri, Evangelos Vassos, Sarah Tosato, Muriel Walshe, Tao Li, Catalina Vasilescu, Thomas W. Mühleisen, August G. Wang, Henrik Ullum, Srdjan Djurovic, Ingrid Melle, Jes Olesen, Lambertus A. Kiemeney, Barbara Franke, GROUP, Chiara Sabatti, Nelson B. Freimer, Jeffrey R. Gulcher, Unnur Thorsteinsdottir, Augustine Kong, Ole A. Andreassen, Roel A. Ophoff, Alexander Georgi, Marcella Rietschel, Thomas Werge, Hannes Petursson, David B. Goldstein, Markus M. Nöthen, Leena Peltonen, David A. Collier, David St Clair, Kari Stefansson & René S. Kahn, Don H. Linszen, Jim van Os, Durk Wiersma, Richard Bruggeman, Wiepke Cahn, Lieuwe de Haan, Lydia Krabbendam & Inez Myin-Germeys for Genetic Risk and Outcome in Psychosis (GROUP)

doi:10.1038/nature07229

See also: Editor's summary | News and Views by Lupski


Rare chromosomal deletions and duplications increase risk of schizophrenia p237

The International Schizophrenia Consortium

doi:10.1038/nature07239

See also: Editor's summary | News and Views by Lupski


RNA interference screen for human genes associated with West Nile virus infection p242

Manoj N. Krishnan, Aylwin Ng, Bindu Sukumaran, Felicia D. Gilfoy, Pradeep D. Uchil, Hameeda Sultana, Abraham L. Brass, Rachel Adametz, Melody Tsui, Feng Qian, Ruth R. Montgomery, Sima Lev, Peter W. Mason, Raymond A. Koski, Stephen J. Elledge, Ramnik J. Xavier, Herve Agaisse & Erol Fikrig

doi:10.1038/nature07207

See also: Editor's summary


T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance p246

Marko Pesu, Wendy T. Watford, Lai Wei, Lili Xu, Ivan Fuss, Warren Strober, John Andersson, Ethan M. Shevach, Martha Quezado, Nicolas Bouladoux, Anton Roebroek, Yasmine Belkaid, John Creemers & John J. O'Shea

doi:10.1038/nature07210

See also: Editor's summary


Heterochromatin links to centromeric protection by recruiting shugoshin p251

Yuya Yamagishi, Takeshi Sakuno, Mari Shimura & Yoshinori Watanabe

doi:10.1038/nature07217

See also: Editor's summary


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Corrigendum

Genome analysis of the platypus reveals unique signatures of evolution p256

Wesley C. Warren, LaDeana W. Hillier, Jennifer A. Marshall Graves, Ewan Birney, Chris P. Ponting, Frank Grützner, Katherine Belov, Webb Miller, Laura Clarke, Asif T. Chinwalla, Shiaw-Pyng Yang, Andreas Heger, Devin P. Locke, Pat Miethke, Paul D. Waters, Frédéric Veyrunes, Lucinda Fulton, Bob Fulton, Tina Graves, John Wallis, Xose S. Puente, Carlos López-Otín, Gonzalo R. Ordóñez, Evan E. Eichler, Lin Chen, Ze Cheng, Janine E. Deakin, Amber Alsop, Katherine Thompson, Patrick Kirby, Anthony T. Papenfuss, Matthew J. Wakefield, Tsviya Olender, Doron Lancet, Gavin A. Huttley, Arian F. A. Smit, Andrew Pask, Peter Temple-Smith, Mark A. Batzer, Jerilyn A. Walker, Miriam K. Konkel, Robert S. Harris, Camilla M. Whittington, Emily S. W. Wong, Neil J. Gemmell, Emmanuel Buschiazzo, Iris M. Vargas Jentzsch, Angelika Merkel, Juergen Schmitz, Anja Zemann, Gennady Churakov, Jan Ole Kriegs, Juergen Brosius, Elizabeth P. Murchison, Ravi Sachidanandam, Carly Smith, Gregory J. Hannon, Enkhjargal Tsend-Ayush, Daniel McMillan, Rosalind Attenborough, Willem Rens, Malcolm Ferguson-Smith, Christophe M. Lefèvre, Julie A. Sharp, Kevin R. Nicholas, David A. Ray, Michael Kube, Richard Reinhardt, Thomas H. Pringle, James Taylor, Russell C. Jones, Brett Nixon, Jean-Louis Dacheux, Hitoshi Niwa, Yoko Sekita, Xiaoqiu Huang, Alexander Stark, Pouya Kheradpour, Manolis Kellis, Paul Flicek, Yuan Chen, Caleb Webber, Ross Hardison, Joanne Nelson, Kym Hallsworth-Pepin, Kim Delehaunty, Chris Markovic, Pat Minx, Yucheng Feng, Colin Kremitzki, Makedonka Mitreva, Jarret Glasscock, Todd Wylie, Patricia Wohldmann, Prathapan Thiru, Michael N. Nhan, Craig S. Pohl, Scott M. Smith, Shunfeng Hou, Mikhail Nefedov, Pieter J. de Jong, Marilyn B. Renfree, Elaine R. Mardis & Richard K. Wilson

doi:10.1038/nature07253


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Erratum

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer p256

Li Ma, Julie Teruya-Feldstein & Robert A. Weinberg

doi:10.1038/nature07316


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Naturejobs

Prospect

Prospects p257

The LHC will both help and hurt research opportunities for high-energy physics in the United States.

Gene Russo

doi:10.1038/nj7210-257a


Special Report

Collision course p258

This month, all eyes in the high-energy-physics community will be on the long-awaited launch of CERN's new particle collider. But US budget cuts and an uncertain job market mean the field has little else to celebrate. Eric Hand reports.

Eric Hand

doi:10.1038/nj7210-258a


Career View

Eric Barron, director, National Center for Atmospheric Research, Boulder, Colorado p260

New NCAR director faces tough decisions early on.

Alexandra Witze

doi:10.1038/nj7210-260a


Fellowships at the FDA p260

FDA fellowship attempts to attract top talent.

Virginia Gewin

doi:10.1038/nj7210-260b


Job transplant p260

I loathe the uprooting – but I look forward to the replanting.

Jon Yearsley

doi:10.1038/nj7210-260c


Highlights

Highlight on Ireland

doi:10.1038/nj0226


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Futures

The whaleblimp herder p262

Transport issues.

Chris Butler

doi:10.1038/455262a


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