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Nature 454, 1054-1055 (28 August 2008) | doi:10.1038/4541054a; Published online 27 August 2008

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Battle of the sexes may set the brain

Christopher Badcock1 & Bernard Crespi2

  1. Christopher Badcock is a reader in sociology at the London School of Economics, Houghton Street, London WC2A 2AE, UK.
  2. Bernard Crespi is professor of evolutionary biology at Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
    Email: crespi@sfu.ca

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A tug-of-war between the mother's and father's genes in the developing brain could explain a spectrum of mental disorders from autism to schizophrenia, suggest Christopher Badcock and Bernard Crespi.

It has long been recognized that mental illnesses such as schizophrenia and autism tend to run in families. But neither disorder obeys classical Mendelian laws of inheritance, making it difficult to pinpoint the genes involved.