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Nature 454, 586-587 (31 July 2008) | doi:10.1038/454586a; Published online 30 July 2008
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Cancer: Ins and outs of tumour control
Maria S. Soengas1
Abstract
When a potentially dangerous cell can't be repaired, it must be either stopped or killed. Premature senescence of cancerous cells is one such 'stop' mechanism, in which immune mediators play an unexpected part.
Various mutations can make normal mammalian cells cancerous. Luckily, several built-in mechanisms that inhibit tumour formation are in place.
- Maria S. Soengas is in the Melanoma Group, Molecular Pathology Programme, Spanish National Cancer Research Centre, Madrid 28029, Spain.
Email: msoengas@cnio.es
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