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Nature 453, 1194-1195 (26 June 2008) | doi:10.1038/4531194a; Published online 25 June 2008
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Drug discovery: A lifeline for suffocating tissues
Massimiliano Mazzone1 & Peter Carmeliet1
Abstract
When a blood vessel becomes blocked, the ideal treatment would be a drug that induces new vessel formation in the damaged tissue, without affecting healthy tissues. With the chemical nitrite, we might be on to a winner.
Ischaemia occurs, for instance, when a blood vessel becomes occluded by a clot. It affects hundreds of millions of people worldwide, and is often life-threatening.
- Massimiliano Mazzone and Peter Carmeliet are in the Vesalius Research Center, University of Leuven, Flanders, Institute for Biotechnology (VIB), B-3000 Leuven, Belgium.
Email: peter.carmeliet@med.kuleuven.be
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