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Nature 453, 993-994 (19 June 2008) | doi:10.1038/453993a; Published online 18 June 2008

Open Innovation Challenges

Medical imaging: Colourful future for MRI

Richard Bowtell1

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Following multiple physiological variables or cell types in vivo requires specific probes. Microfabricated magnetic particles could produce such tuneable contrast agents for magnetic resonance imaging.

Optical imaging routinely uses multicoloured contrast agents ranging from traditional chemical dyes and fluorophores to specially engineered quantum dots. In magnetic resonance imaging (MRI), contrast agents have also proved extremely useful, but their effects are largely indistinguishable from one another, leading to essentially monochrome contrast based on increased or decreased signal strength.

  1. Richard Bowtell is at the Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2RD, UK.
    Email: richard.bowtell@nottingham.ac.uk

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