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Nature 453, 302-305 (15 May 2008) | doi:10.1038/nature07037; Published online 14 May 2008
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Regenerative medicine and human models of human disease
Abstract
Recent advances in stem-cell technology are now allowing the mechanisms of human disease to be studied in human cells. A new era for regenerative medicine is arising from such disease models, extending beyond early cell-based therapies and towards evaluating genetic variation in humans and identifying the molecular pathways that lead to disease, as well as targets for therapy.
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