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Nature 452, 161-162 (13 March 2008) | doi:10.1038/452161a; Published online 12 March 2008

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Physical chemistry: Did life grind to a start?

J. Michael McBride1 & John C. Tully1

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Many solids can adopt two mirror-image crystal forms, and often grow as mixtures of both. A curious mechanism of crystal growth might explain why some mixtures convert into one form when subjected to grinding.

If Alice had been a biochemist, she would have found an even more unfamiliar world on the far side of the looking-glass. In principle, the molecules of life can adopt two mirror-image forms (often described as left- and right-handed), which from a chemical perspective are equally likely to exist.

  1. J. Michael McBride and John C. Tully are in the Department of Chemistry, Yale University, Box 208107, New Haven, Connecticut 06520, USA.
    Email: j.mcbride@yale.edu
    Email: john.tully@yale.edu

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