Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 450, 991-1000 (13 December 2007) | doi:10.1038/nature06525; Published online 12 December 2007
Open Innovation Challenges
- More Challenges
- Powered by:
nature jobs
Assistant Professor of Medicine
- Massachusetts General Hospital
- Boston, MA
Senior Scientific Manager / Chief Scientific Manager for Neuroscience Group In Vivo Pharmacology / Biology
- Syngene International
- Bangalore, Karnataka 560099 India
Review Article The biological impact of mass-spectrometry-based proteomics
Benjamin F. Cravatt1,2, Gabriel M. Simon1,2 & John R. Yates III1
Abstract
In the past decade, there have been remarkable advances in proteomic technologies. Mass spectrometry has emerged as the preferred method for in-depth characterization of the protein components of biological systems. Using mass spectrometry, key insights into the composition, regulation and function of molecular complexes and pathways have been gained. From these studies, it is clear that mass-spectrometry-based proteomics is now a powerful 'hypothesis-generating engine' that, when combined with complementary molecular, cellular and pharmacological techniques, provides a framework for translating large data sets into an understanding of complex biological processes.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Towards quantitative analysis of proteome dynamicsNature Biotechnology News and Views (01 Mar 2007)
Towards quantitative analysis of proteome dynamicsNature Biotechnology News and Views (01 Mar 2007)
Malaria Mass tool for diagnosisNature News and Views (15 Aug 2002)
See all 4 matches for News And Views