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Nature 450, 959-960 (13 December 2007) | doi:10.1038/450959a; Published online 12 December 2007
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Chief Scientific Manager - Medicinal Chemistry
- Syngene International
- Bangalore, Karnataka 560099 India
Research Fellow
- Beth Israel Deaconess Medical Center
- Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215
Molecular biology: Genome under surveillance
Karen M. Arndt1
Abstract
Decoding the information stored in DNA requires an intricate balance between processes that turn gene expression on or off. A protein that influences the packaging of DNA regulates this balance genome-wide.
Organisms store instructions for their own existence in DNA. Specific proteins access and read the DNA sequence either to replicate it or to mediate gene expression.
- Karen M. Arndt is in the Department of Biological Sciences, 269 Crawford Hall, University of Pittsburgh, 4249 Fifth Avenue, Pittsburgh, Pennsylvania 15260, USA.
Email: arndt@pitt.edu
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