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Technology Feature
Nature 450, 1117-1120 (13 December 2007) | doi:10.1038/4501117a; Published online 12 December 2007
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Dean, Faculty of Science
- University of Victoria
- Victoria, British Columbia, Canada
Senior Scientific Manager / Chief Scientific Manager for Metabolic Disorder and Cardiavascular Area In Vivo Pharmacology / Biology
- Syngene International
- Bangalore, Karnataka 560099 India
Small RNAs: Delivering the future
Nathan Blow1
Abstract
Drugs to treat diseases from cancer to AIDS could soon rely on short strands of RNA for their effects. But scientists must first work out how to navigate these fragments around the body. Nathan Blow reports.
The remarkable ability of short sequences of synthetic RNA to interfere with messenger RNA and thereby silence the activity of specific genes has proved incredibly helpful to geneticists wrestling with genetic function. And the push to harness this RNA interference (RNAi) for therapeutic use is now beginning to make headway.
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