Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 450, 621-622 (29 November 2007) | doi:10.1038/450621a; Published online 28 November 2007
Cell biology: Pore puzzle
John D. Aitchison1 & Richard W. Wozniak2
Abstract
Where would you start in trying to work out the structure of a macromolecular machine consisting of 456 proteins? Taking a combined experimental and computational approach is one answer.
Consider a 1,000-piece jigsaw puzzle. There are millions of ways in which the pieces might fit together, yet there is only one solution.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Determining the architectures of macromolecular assembliesNature Article (29 Nov 2007)
The molecular architecture of the nuclear pore complexNature Article (29 Nov 2007)
Minimal nuclear pore complexes define FG repeat domains essential for transportNature Cell Biology Article (01 Mar 2004)