Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 450, 355-356 (15 November 2007) | doi:10.1038/450355a; Published online 14 November 2007
Open Innovation Challenges
-
Methods to Analyze Consumer Emotions
The Seeker is looking for methods to analyze consumer emotions. This Challenge requires only a writ...
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
nature jobs
Assistant Professor
- University of Texas
- Austin TX United States
Full-Professor of Heart and Thoracic Surgery (W3) (f / m)
- Friedrich-Schiller-University Jena
- Jena Germany
Structural biology: A receptor unlocked
Stephen R. Sprang1
Abstract
G-protein-coupled receptors govern many biological functions, yet little is known about the molecular basis of their activity. The structure of a prominent example of these receptors is now revealed.
The pounding heart and speeding metabolism that accompany fear and fury are the work of the adrenaline molecule, which is produced by the adrenal gland at times of stress. Adrenaline is an agonist — an activator — of
2-adrenergic receptors (
2ARs).
- Stephen R. Sprang is at the Center for Biomolecular Structure and Dynamics, University of Montana, Missoula, Montana 59812, USA.
Email: stephen.sprang@umontana.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
A crystal clear view of the β2-adrenergic receptorNature Biotechnology News and Views (01 Feb 2008)
Structural biology A moving story of receptorsNature News and Views (25 Sep 2008)
See all 5 matches for News And ViewsRESEARCH
Crystal structure of the ligand-free G-protein-coupled receptor opsinNature Article (10 Jul 2008)
Structure of a &bgr; 1 -adrenergic G-protein-coupled receptorNature Article (24 Jul 2008)
See all 9 matches for Research
