Supplementary information

From the following article:

Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1

Eros Lazzerini Denchi & Titia de Lange

Nature 448, 1068-1071(30 August 2007)

doi:10.1038/nature06065

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Supplementary Figures

This file contains Supplementary Figures S1-S9 with Legends. Figures S1-S5 show gammaH2AX TIFs (S1), ChIP for shelterin (S2), ATR-independent DNA damage response (S3), ATM-dependent NEHJ (S4-S5) following TRF2 deletion. Figures S6-S7 show activation of ATR but not ATM upon POT1 inhibition. Figures S8-S9 show TIF formation and NHEJ in TRF2-/- ATM-/- cells upon POT1 inhibition.

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