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Inflammatory disease

Assault on the guardian

In multiple sclerosis, the immune system attacks 'self' tissues. Ten years after the discovery of one target of this autoimmunity, work with mice identifies it as a guardian protein produced in response to inflammation.

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Ransohoff, R. Assault on the guardian. Nature 448, 421–422 (2007). https://doi.org/10.1038/448421a

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