Table of contents
Volume 447 Number 7140 pp1-114
(this content only available online) indicates content that is available online only
Editorials
South Africa's AIDS plan p1
A strategic plan has been developed to tackle the nation's HIV crisis — at last.
doi:10.1038/447001a
Share your lab notes p1
The use of electronic laboratory notebooks should be supported by all concerned.
doi:10.1038/447001b
Hard to defend p2
US missile defence plans require scrutiny.
doi:10.1038/447002a
News
The race to wire up the poor p6
Crunch time for One Laptop Per Child scheme.
Declan Butler
doi:10.1038/447006a
Long odds on a long shadow p7
Astronomers take a gamble on Earth-like planet.
Katharine Sanderson
doi:10.1038/447007a
Artefacts in ocean data hide rising temperatures p8
Software glitch gave wrong readings.
Quirin Schiermeier
doi:10.1038/447008a
Reform makes Italian research accountable p8
Institutions finally gain autonomy and take on responsibilities.
Alison Abbott
doi:10.1038/447008b
India plans third Antarctic base p9
International community to look at proposal afresh.
K. S. Jayaraman
doi:10.1038/447009a
Missing gas saps plant theory p11
Botanists find no evidence for methane emissions.
Michael Hopkin
doi:10.1038/447011a
Sidelines p11
doi:10.1038/447011b
Denmark launches big push for protein power p12
Copenhagen centre will focus on human disease.
Alison Abbott
doi:10.1038/447012a
Rapid sequencer puts virus in the frame for deaths p12
But researchers warn speed needs to be matched with certainty.
Heidi Ledford
doi:10.1038/447012b
Live Earth taps into sense of joy p13
Rock 'n' roll and the movies join the fight against climate change.
Emma Marris
doi:10.1038/447013a
Business
Patenting the obvious? p16
A patent ruling has delivered a serious blow to one US state's hopes of a biotechnology boom. Erika Check reports.
doi:10.1038/447016a
See also: Editor's summary
In brief p17
doi:10.1038/447017a
Market watch p17
Colin Macilwain
doi:10.1038/447017b
News Features
Brain craze p18
Neuroscientist Ryuta Kawashima promotes the idea that computer games can boost the ageing brain — but others in the field remain sceptical. Ichiko Fuyuno investigates.
doi:10.1038/447018a
See also: Editor's summary
Archaeology: Deep divisions p22
Archaeologists are unearthing remarkable finds in Jerusalem. But the digs have sparked an argument over who should run the site and present the results to the public. Haim Watzman reports.
doi:10.1038/447022a
See also: Editor's summary
HIV: A tale of two centres p26
Two institutes on opposite sides of South Africa are intent on tackling HIV. But they are separated by more than geographical distance, finds Michael Cherry.
doi:10.1038/447026a
Correspondence
Long shadow of Linnaeus's human taxonomy p28
Jonathan Marks
doi:10.1038/447028a
Brain drain: gains all round when it goes both ways p28
Volker Heine
doi:10.1038/447028b
Brain drain: poor countries lose most and benefit least p28
Andrew Isaac Meso
doi:10.1038/447028c
Spring Books
A strange sense of self p29
Am I a mirage?
Susan Blackmore reviews I Am a Strange Loop by Douglas R. Hofstadter
doi:10.1038/447029a
See also: Editor's summary
James Bond with a feather duster p30
Kathleen Taylor reviews The Canon: A Whirligig Tour of the Beautiful Basics of Science by Natalie Angier
doi:10.1038/447030a
See also: Editor's summary
The dark heart of the bomb p31
John S. Rigden reviews Plutonium: A History of the World's Most Dangerous Element by Jeremy Bernstein
doi:10.1038/447031a
See also: Editor's summary
Trouble in paradise p33
Daniel Pauly reviews Coral: A Pessimist in Paradise by Steve Jones
doi:10.1038/447033a
See also: Editor's summary
Unearthing gender issues p34
Pat Shipman reviews The Invisible Sex: Uncovering The True Roles Of Woman In Prehistory by J. M. Adovasio, Olga Soffer & Jake Page
doi:10.1038/447034a
See also: Editor's summary
When the numbers don't add up p35
Roger Pielke, Jr reviews Useless Arithmetic: Why Environmental Scientists Can't Predict the Future by Orrin Pilkey & Linda Pilkey-Jarvis
doi:10.1038/447035a
See also: Editor's summary
Science set in stone p37
Per E. Ahlberg reviews Swimming in Stone: The Amazing Gogo Fossils of the Kimberley by John Long
doi:10.1038/447037a
See also: Editor's summary
An ode to symmetry p38
Joseph Mazur reviews Why Beauty Is Truth: The History of Symmetry by Ian Stewart
doi:10.1038/447038a
See also: Editor's summary
Essay
ConnectionsThe best is yet to come p39
Optimality is a key organizing principle of science, but the patterns of connections within real-world networks do not always respect it.
Mark Buchanan
doi:10.1038/447039a
News and Views
Mathematics: A beauty and a beast p41
The mapping of the largest exceptional Lie group, E8, is a milestone for enthusiasts for the aesthetics of mathematics. But this embodiment of complex symmetry could be of interest to fundamental physics, too.
Hermann Nicolai
doi:10.1038/447041a
Chemical Biology: Ignore the nonsense p42
A small molecule forces the protein-translation machinery to overlook the signals that would otherwise result in its premature termination. Genuine stop signs are, however, read and obeyed.
Anton Schmitz & Michael Famulok
doi:10.1038/nature05715
See also: Editor's summary
Particle physics: Wobbly oscillations p43
Neutrinos seem to oscillate: they change back and forth between one type and another and, by extension, have a tiny mass. But one experiment that predicted a particularly large mass looks to have been mistaken.
David Wark
doi:10.1038/447043a
Neuroscience: Unconscious networking p46
What are neural networks doing when the brain is at rest? It turns out that in primates, even under conditions of deep anaesthesia, some of these networks undergo highly organized patterns of activity.
Mark A. Pinsk & Sabine Kastner
doi:10.1038/447046a
See also: Editor's summary
Nuclear chemistry: Panning for ununbium p47
The chemical identification of two atoms of element 112 — scooped from the helium stream they were suspended in using a gold pan — brings the superheavy elements' fabled island of stability into sharper focus.
Andreas Türler
doi:10.1038/447047a
See also: Editor's summary
Earthquakes: Relationships in a slow slip p49
The size and duration of disparate, slow, low-amplitude earthquake processes seem to obey a single scaling law. The relationship is very different from that which governs their more violent and impulsive cousins.
Heidi Houston & John E. Vidale
doi:10.1038/447049a
See also: Editor's summary
Materials science: Nanotubes see the light p50
When it comes to having their conduction properties tweaked, carbon nanotubes are bothersome customers. One way to do it is to incorporate a photosensitive dye into the nanotubes' walls.
Dirk M. Guldi
doi:10.1038/447050a
Correction p51
doi:10.1038/447051a
50 & 100 Years Ago p51
doi:10.1038/447051b
Obituary: F. Clark Howell (1925–2007) p52
Palaeoanthropologist who defined a discipline.
Tim D. White
doi:10.1038/447052a
Brief Communications Arising
Palaeoclimatology: Evidence for hot early oceans? pE1
Graham A. Shields & James F. Kasting
doi:10.1038/nature05830
First paragraph | Full Text | PDF (103K)
Palaeoclimatology: Evidence for hot early oceans? (Reply) pE1
François Robert & Marc Chaussidon
doi:10.1038/nature05831
First paragraph | Full Text | PDF (103K)
Articles
An integrated model of kimberlite ascent and eruption p53
Lionel Wilson & James W. Head III
doi:10.1038/nature05692
Abstract | Full Text | PDF (362K)
The structure of a plant photosystem I supercomplex at 3.4 Å resolution p58
Alexey Amunts, Omri Drory & Nathan Nelson
doi:10.1038/nature05687
Abstract | Full Text | PDF (1,095K) | Supplementary information
See also: Editor's summary
Letters
High-resolution subsurface water-ice distributions on Mars p64
Joshua L. Bandfield
doi:10.1038/nature05781
First paragraph | Full Text | PDF (561K) | Supplementary information
See also: Editor's summary
Direct measurement of antiferromagnetic domain fluctuations p68
O. G. Shpyrko, E. D. Isaacs, J. M. Logan, Yejun Feng, G. Aeppli, R. Jaramillo, H. C. Kim, T. F. Rosenbaum, P. Zschack, M. Sprung, S. Narayanan & A. R. Sandy
doi:10.1038/nature05776
First paragraph | Full Text | PDF (651K) | Supplementary information
See also: Editor's summary
Chemical characterization of element 112 p72
R. Eichler, N. V. Aksenov, A. V. Belozerov, G. A. Bozhikov, V. I. Chepigin, S. N. Dmitriev, R. Dressler, H. W. Gäggeler, V. A. Gorshkov, F. Haenssler, M. G. Itkis, A. Laube, V. Ya. Lebedev, O. N. Malyshev, Yu. Ts. Oganessian, O. V. Petrushkin, D. Piguet, P. Rasmussen, S. V. Shishkin, A. V. Shutov, A. I. Svirikhin, E. E. Tereshatov, G. K. Vostokin, M. Wegrzecki & A. V. Yeremin
doi:10.1038/nature05761
First paragraph | Full Text | PDF (248K) | Supplementary information
See also: Editor's summary | News and Views by Türler
A scaling law for slow earthquakes p76
Satoshi Ide, Gregory C. Beroza, David R. Shelly & Takahiko Uchide
doi:10.1038/nature05780
First paragraph | Full Text | PDF (2,064K)
See also: Editor's summary | News and Views by Houston & Vidale
Drought sensitivity shapes species distribution patterns in tropical forests p80
Bettina M. J. Engelbrecht, Liza S. Comita, Richard Condit, Thomas A. Kursar, Melvin T. Tyree, Benjamin L. Turner & Stephen P. Hubbell
doi:10.1038/nature05747
First paragraph | Full Text | PDF (419K) | Supplementary information
See also: Editor's summary
Intrinsic functional architecture in the anaesthetized monkey brain p83
J. L. Vincent, G. H. Patel, M. D. Fox, A. Z. Snyder, J. T. Baker, D. C. Van Essen, J. M. Zempel, L. H. Snyder, M. Corbetta & M. E. Raichle
doi:10.1038/nature05758
First paragraph | Full Text | PDF (795K) | Supplementary information
See also: Editor's summary | News and Views by Pinsk & Kastner
PTC124 targets genetic disorders caused by nonsense mutations p87
Ellen M. Welch, Elisabeth R. Barton, Jin Zhuo, Yuki Tomizawa, Westley J. Friesen, Panayiota Trifillis, Sergey Paushkin, Meenal Patel, Christopher R. Trotta, Seongwoo Hwang, Richard G. Wilde, Gary Karp, James Takasugi, Guangming Chen, Stephen Jones, Hongyu Ren, Young-Choon Moon, Donald Corson, Anthony A. Turpoff, Jeffrey A. Campbell, M. Morgan Conn, Atiyya Khan, Neil G. Almstead, Jean Hedrick, Anna Mollin, Nicole Risher, Marla Weetall, Shirley Yeh, Arthur A. Branstrom, Joseph M. Colacino, John Babiak, William D. Ju, Samit Hirawat, Valerie J. Northcutt, Langdon L. Miller, Phyllis Spatrick, Feng He, Masataka Kawana, Huisheng Feng, Allan Jacobson, Stuart W. Peltz & H. Lee Sweeney
doi:10.1038/nature05756
First paragraph | Full Text | PDF (579K) | Supplementary information
See also: Editor's summary | News and Views by Schmitz & Famulok
Chitin induces accumulation in tissue of innate immune cells associated with allergy p92
Tiffany A. Reese, Hong-Erh Liang, Andrew M. Tager, Andrew D. Luster, Nico Van Rooijen, David Voehringer & Richard M. Locksley
doi:10.1038/nature05746
First paragraph | Full Text | PDF (821K) | Supplementary information
See also: Editor's summary
A positive feedback mechanism governs the polarity and motion of motile cilia p97
Brian Mitchell, Richard Jacobs, Julie Li, Shu Chien & Chris Kintner
doi:10.1038/nature05771
First paragraph | Full Text | PDF (829K) | Supplementary information
Template switching during break-induced replication p102
Catherine E. Smith, Bertrand Llorente & Lorraine S. Symington
doi:10.1038/nature05723
First paragraph | Full Text | PDF (615K) | Supplementary information
A pre-existing hydrophobic collapse in the unfolded state of an ultrafast folding protein p106
K. Hun Mok, Lars T. Kuhn, Martin Goez, Iain J. Day, Jasper C. Lin, Niels H. Andersen & P. J. Hore
doi:10.1038/nature05728
First paragraph | Full Text | PDF (1,493K) | Supplementary information
Naturejobs
ProspectAs biotech jobs continue to grow, potential employees should examine the company's product pipeline. p111
Paul Smaglik
doi:10.1038/nj7140-111a
Career Views
Klaus Stöhr, director of the influenza vaccine franchises, Novartis Vaccines and Diagnostics, Cambridge, Massachusetts p112
Klaus Stöhr moves from the WHO to industry.
Virginia Gewin
doi:10.1038/nj7140-112a
Gem of an idea for a unique machine p112
The merits of using biological circuits to get students excited about synthetic biology.
Michael Strong & George Church
doi:10.1038/nj7140-112b
The balancing act p112
Postdocs are the ultimate circus performers.
Maria Ocampo-Hafalla
doi:10.1038/nj7140-112c
Recruitment
Dr Jekyll and Ms Hide p114
Where are the women in science? And what would attract them from other sectors?
Jan Bogg
doi:10.1038/nj7140-114a
Highlights
Opportunities: The National Institutes of Health
doi:10.1038/nj0158