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Nature 446, 588-589 (5 April 2007) | doi:10.1038/446588a; Published online 4 April 2007

Proteins make light work of nerve control

Alison Abbott

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Simple switch promises revolution in neuroscience.

There were audible gasps and spontaneous applause at a neuroscience meeting in Salt Lake City, Utah, in February, when Ed Boyden described a protein that switches off nerve firing when activated by light. And when Karl Deisseroth told the fuller story of the protein, called NpHR and published in this week's Nature, at Cold Spring Harbor in New York late last month, there was talk of a revolution in neuroscience.

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