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Nature 445, 828-830 (22 February 2007) | doi:10.1038/nature05568; Published online 11 February 2007

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Human genetics: Variants in common diseases

Nelson B. Freimer1 & Chiara Sabatti2

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Most common diseases arise from interaction between multiple genetic variations and factors such as diet. Studies of such diseases that exploit the rich data on variation in the human genome are just beginning.

The results of the first genome-wide-association (GWA) surveys of common diseases are trickling out. This trickle will soon be a flood of data, much anticipated but challenging to interpret.

  1. Nelson B. Freimer is in the UCLA Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, 695 Charles Young Drive South, Los Angeles, California 90095-1761, USA.
    Email: nfreimer@mednet.ucla.edu
  2. Chiara Sabatti is in the UCLA Departments of Human Genetics and Statistics, 695 Charles Young Drive South, Los Angeles, California 90095-7088, USA.
    Email: csabatti@mednet.ucla.edu

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