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Developmental biology

Cell fate in the mammary gland

Nature volume 445, pages 724–726 (2007)Cite this article

Most breast cancers have their origin in the luminal epithelial cells of the mammary gland. Defining how a master regulator controls the development of this cell lineage could provide important hints about why this should be.

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Figure 1: Role of GATA-3 in mammary-gland development.

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Authors and Affiliations

  1. Qiang Tong is in the USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas 77030, USA. qtong@bcm.tmc.edu,

    Qiang Tong

  2. Gökhan S. Hotamisligil is in the Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA. ghotamis@hsph.harvard.edu,

    Gökhan S. Hotamisligil

Authors
  1. Qiang Tong
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  2. Gökhan S. Hotamisligil
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Tong, Q., Hotamisligil, G. Cell fate in the mammary gland. Nature 445, 724–726 (2007). https://doi.org/10.1038/445724a

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