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Nature 445, 609 (8 February 2007) | doi:10.1038/nature05566; Published online 21 January 2007

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Structural biology: Molecular machinery in action

Ad Bax1 & Dennis A. Torchia1

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Nuclear magnetic resonance is the best way to study motion in proteins, but it could be applied only to small systems. This limitation has been overcome to reveal the dynamics of a large protein complex.

If biology were a car, structural biologists would be looking under the bonnet to find out how the engine works. Put more prosaically, structural biology aims to understand how biology works at the molecular level.

  1. Ad Bax and Dennis A. Torchia are at the National Institutes of Health, Bethesda, Maryland 20892, USA.
    Email: bax@nih.gov
    Email: dtorchia@mail.nih.gov

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