The complement C3 protein binds to pathogens, singling them out for execution by the immune system. Structural studies show how the chemical group responsible for this binding is exposed on activation.
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Carroll, M. Exposure of an executioner. Nature 444, 159–160 (2006). https://doi.org/10.1038/nature05307
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DOI: https://doi.org/10.1038/nature05307