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Nature 442, 517-518 (3 August 2006) | doi:10.1038/442517a; Published online 2 August 2006
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Postdoctoral Fellows
- The Mathematical Biosciences Institute
- Ohio, USA
Scientist (Bioinformatics)
- Polyclone Bioservices Pvt. Ltd
- Bangalore India
Chemical biology: Cutting out the middle man
Tom W. Muir1
Abstract
Wouldn't it be nice if you could control the function of any protein with one small molecule? Unlikely as it sounds, this could become possible through a crafty process known as protein splicing.
One of the most exciting things about chemical biology is its potential to develop new tools for probing cellular processes. Small 'drug-like' molecules that can diffuse into cells and quickly elicit a discernible response offer distinct advantages over genetics-based approaches for exploring the highly choreographed inner workings of a cell1.
- Tom W. Muir is at the Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.
Email: muirt@rockefeller.edu
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