Supplementary information

From the following article:

Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography

Jun Liu, Dianne W. Taylor, Elena B. Krementsova, Kathleen M. Trybus and Kenneth A. Taylor

Nature 442, 208-211(13 July 2006)

doi:10.1038/nature04719

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Supplementary Notes

This file contains Supplementary Movie Legends and Supplementary Figure Legends. This file also contains Supplementary Methods (model fitting, Electron micrographs of actin decorated with myosin V in the inhibited conformation and a description of the conditions used to make the specimens of myoV decorated actin.

Supplementary Figures

Contains a slide show presentation showing the initial models, initial dockings and final results of flexible fitting

Supplementary Movie 1

Shows a tilt series of one of the myosin V 2-D arrays and an image of the tomogram obtained from it.

Supplementary Movie 2

Shows the flower motif density envelope and the fitted atomic model with rotation and different degrees of zoom.

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