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Nature 441, 939-940 (22 June 2006) | doi:10.1038/441939a; Published online 21 June 2006

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Cell biology: The Golgi grows up

Vivek Malhotra1 & Satyajit Mayor2

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The Golgi apparatus of the cell has long baffled biologists, mainly because it is unclear how proteins are conveyed through it on their way to the cell surface. Some innovative microscopy may resolve the issue.

The Golgi apparatus is the enigmatic organelle responsible for modifying newly synthesized proteins that are destined to be secreted from the cell. Discovered by Camillo Golgi in 1898, the apparatus consists of a stack of disc-shaped membranes called cisternae.

  1. Vivek Malhotra is in the Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, California 92014, USA.
  2. Satyajit Mayor is at the National Centre for Biological Sciences, Bangalore 560 065, India.
    Email: vivek@biomail.ucsd.edu

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