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Nature 441, 824 (15 June 2006) | doi:10.1038/441824a; Published online 14 June 2006

Obituary: Bruce Merrifield (1921–2006)

Stephen Kent1

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Inventor of solid-phase peptide synthesis.

The death of Bruce Merrifield on 14 May 2006 brings to a close the life of one of the most original scientists of the second half of the twentieth century. Between 1959 and 1963, Merrifield revolutionized organic chemistry by his invention of solid-phase peptide synthesis.

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