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News and Views
Nature 441, 819-820 (15 June 2006) | doi:10.1038/441819a; Published online 14 June 2006
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Metabolomics Scientist in Nutrition
- Nestle Research Center
- Lausanne Switzerland
Neuroscience Faculty Positions
- University of Tennessee Health Science Center
- Memphis, Tennessee, USA
Neurodegeneration: Good riddance to bad rubbish
Daniel J. Klionsky1
Abstract
Autophagy — cellular 'self-eating' — can be induced by stress, but it also acts continuously in a housekeeping role, disposing of unwanted proteins. Can it protect against neurodegenerative diseases?
Alzheimer's, Parkinson's and Huntington's diseases are names we hear with a certain dread. These devastating illnesses, typically associated with ageing, result from the death of neurons.
- Daniel J. Klionsky is in the Life Sciences Institute, Department of Molecular, Cellular and Developmental Biology, and the Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.
Email: klionsky@umich.edu
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