Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 441, 819-820 (15 June 2006) | doi:10.1038/441819a; Published online 14 June 2006
Open Innovation Challenges
-
Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
-
Efficient Chromosome Doubling: Plant Cell Division
The Seeker is looking for an efficient chromosome doubling method in plants and in particular, metho...
- More Challenges
- Powered by:
nature jobs
Principal Scientist for Development of Solid Dosage Forms
- Novo Nordisk
- Bagsværd, Denmark
Ramalingaswami Fellowship
- Department of Biotechnology
- New Delhi India
Neurodegeneration: Good riddance to bad rubbish
Daniel J. Klionsky1
Abstract
Autophagy — cellular 'self-eating' — can be induced by stress, but it also acts continuously in a housekeeping role, disposing of unwanted proteins. Can it protect against neurodegenerative diseases?
Alzheimer's, Parkinson's and Huntington's diseases are names we hear with a certain dread. These devastating illnesses, typically associated with ageing, result from the death of neurons.
- Daniel J. Klionsky is in the Life Sciences Institute, Department of Molecular, Cellular and Developmental Biology, and the Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.
Email: klionsky@umich.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Stimulating the cell's appetite for itselfNature Chemical Biology News and Views (01 Jun 2007)
Starved cells eat ribosomesNature Cell Biology News and Views (01 May 2008)
See all 7 matches for News And ViewsRESEARCH
Is the nitric oxide system involved in genetic hypertension in Dahl rats?Kidney International Original Article
Suppression of basal autophagy in neural cells causes neurodegenerative disease in miceNature Letters to Editor (15 Jun 2006)
See all 27 matches for Research