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Nature 440, 1121-1122 (27 April 2006) | doi:10.1038/4401121a; Published online 26 April 2006

Molecular biology: Singled out for integration

Michael Chandler1

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Bacteria regularly swap genes among themselves. The structure of an enzyme that mediates the spread of certain DNA elements reveals the unusual way in which they take up residence in new genomes.

The transfer of genes among bacteria is crucial in generating diversity, allowing bacteria to adapt quickly to changing environments. Mobile DNA elements called integron cassettes are major vehicles in such gene exchange.

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RESEARCH

Structural basis for broad DNA-specificity in integron recombination

Nature Article (27 Apr 2006)

Integron cassette insertion: a recombination process involving a folded single strand substrate

The EMBO Journal Article (21 Dec 2005)

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Nature Reviews Microbiology Correspondence (01 Dec 2006)

What are superintegrons?

Nature Reviews Microbiology Correspondence (01 Feb 2007)

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