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Figures and Tables

From the following article:

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

Dae-Kyun Ro, Eric M. Paradise, Mario Ouellet, Karl J. Fisher, Karyn L. Newman, John M. Ndungu, Kimberly A. Ho, Rachel A. Eachus, Timothy S. Ham, James Kirby, Michelle C. Y. Chang, Sydnor T. Withers, Yoichiro Shiba, Richmond Sarpong and Jay D. Keasling

Nature 440, 940-943 (13 April 2006)

doi:10.1038/nature04640

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Schematic representation of the engineered artemisinic acid biosynthetic pathway in S. cerevisiae strain EPY224 expressing CYP71AV1 and CPR.

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Figure 2

Production of amorphadiene by S. cerevisiae strains.

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Figure 3

GC–MS analysis of artemisinic acid produced from A. annua and transgenic yeast.

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Figure 4

In vitro enzyme assays for CYP71AV1 activities.

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