Table of contents


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Editorials

Science under attack p891

Researchers are increasingly upset with the Bush administration, not for its tactics but for its entire operational philosophy.

doi:10.1038/439891a


Not picture-perfect p891

Nature's new guidelines for digital images encourage openness about the way data are manipulated.

doi:10.1038/439891b


Diplomatic incident p892

Japan has fumbled its row with North Korea over tests to identify abductees.

doi:10.1038/439892a


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Research Highlights

Research highlights p894

doi:10.1038/439894a


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News

US scientists fight political meddling p896

Nobel laureate attacks government's suppression of research findings.

Colin Macilwain and Geoff Brumfiel

doi:10.1038/439896a


Culture of fear reigns at Australian research lab p896

Protests grow over claims of academic censorship.

Carina Dennis

doi:10.1038/439896b


Y chromosome fuels dynastic dilemma p898

Genetics of the Japanese imperial succession examined.

David Cyranoski

doi:10.1038/439898a


Oil-rig staff get into marine biology p899

Industry deep-sea vehicles double as explorers.

Jim Giles

doi:10.1038/439899a


Frosty US visa policy leaves Indian science cold p901

Travel restrictions cast shadow over research alliance.

K. S. Jayaraman

doi:10.1038/439901a


Sidelines p901

doi:10.1038/439901b


Grizzlies, dodos and Gore put science on film p902

Ex-vice-president taps into trend towards movies with a message.

Emma Marris

doi:10.1038/439902a


Unrest returns to confront Harvard president p903

Larry Summers' leadership faces fresh challenge.

Helen Pearson

doi:10.1038/439903a


News in brief p904

doi:10.1038/439904a


Correction p904

doi:10.1038/439904b


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News Features

Marine science: Boiling points p905

Teams of researchers are finding vents in ocean floors around the globe. Christina Reed follows the hunt for these extreme ecosystems.

doi:10.1038/439905a

See also: Editor's summary


Agriculture and environment: How green was my subsidy? p908

Europe pumps large quantities of cash into schemes that encourage less-intensive farming. But, finds John Whitfield, some researchers are not sure what benefits they deliver.

doi:10.1038/439908a

See also: Editor's summary


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Business

Rumblings from the fringe p910

The European Patent Office could fall victim of its own success, as threatened national offices attempt to claw back some influence. Alison Abbott reports.

Alison Abbott

doi:10.1038/439910a


In brief p911

doi:10.1038/439911a


Market watch p911

Helen Pearson

doi:10.1038/439911b


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Correspondence

Public repositories need serious funding p912

Bela Tiwari, Dawn Field and Jason Snape

doi:10.1038/439912a


Public repositories: users reluctant to give materials p912

Roderick A. F. MacLeod and Hans G. Drexler

doi:10.1038/439912b


Diet's healthy blend of science and practicality p912

Alastair Robertson

doi:10.1038/439912c


What goes around comes around in drug discovery p912

Robin Spencer, Kelly Longo and John Lowe

doi:10.1038/439912d


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Books and Arts

The changing face of Arab culture p913

Studies of the differences between people can shed light on the rise of Islamism in the Middle East.

Robert Springborg reviews The Middle East: A Cultural Psychology by Gary S. Gregg

doi:10.1038/439913a


Feathered friends p914

Alex Kacelnik reviews In the Company of Crows and Ravens by John R. Marzluff and Tony Angell and Crows: Encounters with the Wise Guys of the Avian World by Candace Savage

doi:10.1038/439914a


In the beginning p915

Leslie Orgel reviews Genesis: The Scientific Quest for Life's Origins by Robert M. Hazen

doi:10.1038/439915a

See also: Editor's summary


Science in culture: Bauhaus at the zoo p916

Modernist designers in the 1930s found inspiration in the life sciences.

Peder Anker

doi:10.1038/439916a


Top

Essay

Family values in black and white p917

The sexual behaviour of penguins, although fascinating, does not offer the moral lessons that some popular commentators would have us believe.

Marlene Zuk

doi:10.1038/439917a

See also: Editor's summary


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News and Views

Quantum information: To compute or not to compute? p919

Quantum physics aims another blow at common sense: a simple quantum computer gives the right answer, even when it is not run. (Traditionalists be comforted: the computer must be turned on.)

Jonathan P. Dowling

doi:10.1038/439919a


Neurobiology: Efficiency measures p920

The nervous system translates sensory information into electrical impulses. The neural 'code' involved seems to represent natural sounds and images efficiently, using the smallest number of impulses.

Michael R. DeWeese and Anthony Zador

doi:10.1038/439920a


Particle physics: Quarks on a gravitational string p921

Quantum chromodynamics, the theory of the strong nuclear force, is notoriously intractable. An alternative approach brings gravity to bear, and produces fairly accurate predictions of some physical quantities.

Nick Evans

doi:10.1038/439921a


Evolution: Careful with that amphioxus p923

The textbook tale of vertebrate origins is brought into question by phylogenetic analyses of new genomic data. But the amphioxus, long viewed as a precursor to fish, remains a central character in events.

Henry Gee

doi:10.1038/439923a

See also: Editor's summary


Planetary science: Pluto's expanding brood p924

Pluto is no lone ranger in the farthest expanses of the Solar System — its travelling companions now number three. And if Pluto can have so many, why shouldn't other objects in the distant, icy Kuiper belt?

Richard P. Binzel

doi:10.1038/439924a


50 & 100 years ago p925


Marine biology: Spawning spot p926

Rosalind Cotter

doi:10.1038/439926a

See also: Editor's summary


Parasitology: Switching like for like p926

To remain hidden from its host's immune system, the malaria parasite must vary the proteins on the surface of the infected cell. The genes encoding these proteins are very similar, so how does the parasite express just one at a time?

Piet Borst and Paul-André Genest

doi:10.1038/439926b

See also: Editor's summary


Corrections p927

doi:10.1038/439927a


Corrections p927

doi:10.1038/439927b


Corrections p927

doi:10.1038/439927c


Obituary: Nicholas Shackleton (1937–2006) p928

A founding father of palaeoclimatology, and an avid clarinettist.

Gerald H. Haug and Larry C. Peterson

doi:10.1038/439928a


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Brief Communications

Oceanic biology: Spawning of eels near a seamount p929

Tiny transparent larvae of the Japanese eel collected in the open ocean reveal a strategic spawning site.

Katsumi Tsukamoto

doi:10.1038/439929a

See also: Editor's summary


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Review

A new radiocarbon revolution and the dispersal of modern humans in Eurasia p931

Paul Mellars

doi:10.1038/nature04521

See also: Editor's summary


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Article

Adaptive filtering enhances information transmission in visual cortex p936

Tatyana O. Sharpee, Hiroki Sugihara, Andrei V. Kurgansky, Sergei P. Rebrik, Michael P. Stryker and Kenneth D. Miller

doi:10.1038/nature04519

See also: News and Views by DeWeese & Zador


Top

Letters

Discovery of two new satellites of Pluto p943

H. A. Weaver, S. A. Stern, M. J. Mutchler, A. J. Steffl, M. W. Buie, W. J. Merline, J. R. Spencer, E. F. Young and L. A. Young

doi:10.1038/nature04547

See also: Editor's summary | News and Views by Binzel


A giant impact origin for Pluto's small moons and satellite multiplicity in the Kuiper belt p946

S. A. Stern, H. A. Weaver, A. J. Steffl, M. J. Mutchler, W. J. Merline, M. W. Buie, E. F. Young, L. A. Young and J. R. Spencer

doi:10.1038/nature04548

See also: Editor's summary | News and Views by Binzel


Counterfactual quantum computation through quantum interrogation p949

Onur Hosten, Matthew T. Rakher, Julio T. Barreiro, Nicholas A. Peters and Paul G. Kwiat

doi:10.1038/nature04523

See also: Editor's summary | News and Views by Dowling


Quantum supercurrent transistors in carbon nanotubes p953

Pablo Jarillo-Herrero, Jorden A. van Dam and Leo P. Kouwenhoven

doi:10.1038/nature04550


Magnetic-field-induced shape recovery by reverse phase transformation p957

R. Kainuma, Y. Imano, W. Ito, Y. Sutou, H. Morito, S. Okamoto, O. Kitakami, K. Oikawa, A. Fujita, T. Kanomata and K. Ishida

doi:10.1038/nature04493


Aluminium control of argon solubility in silicate melts under pressure p961

M. Ali Bouhifd and Andrew P. Jephcoat

doi:10.1038/nature04583


Tunicates and not cephalochordates are the closest living relatives of vertebrates p965

Frédéric Delsuc, Henner Brinkmann, Daniel Chourrout and Hervé Philippe

doi:10.1038/nature04336

See also: Editor's summary | News and Views by Gee


Parasitic plants indirectly regulate below-ground properties in grassland ecosystems p969

Richard D. Bardgett, Roger S. Smith, Robert S. Shiel, Simon Peacock, Janet M. Simkin, Helen Quirk and Phil J. Hobbs

doi:10.1038/nature04197

See also: Editor's summary


Facioscapulohumeral muscular dystrophy in mice overexpressing FRG1 p973

Davide Gabellini, Giuseppe D'Antona, Maurizio Moggio, Alessandro Prelle, Chiara Zecca, Raffaella Adami, Barbara Angeletti, Patrizia Ciscato, Maria Antonietta Pellegrino, Roberto Bottinelli, Michael R. Green and Rossella Tupler

doi:10.1038/nature04422

See also: Editor's summary


Efficient auditory coding p978

Evan C. Smith and Michael S. Lewicki

doi:10.1038/nature04485

See also: News and Views by DeWeese & Zador


Fast vesicle reloading and a large pool sustain high bandwidth transmission at a central synapse p983

Chiara Saviane and R. Angus Silver

doi:10.1038/nature04509


NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia p988

I. Micu, Q. Jiang, E. Coderre, A. Ridsdale, L. Zhang, J. Woulfe, X. Yin, B. D. Trapp, J. E. McRory, R. Rehak, G. W. Zamponi, W. Wang and P. K. Stys

doi:10.1038/nature04474


Purification and unique properties of mammary epithelial stem cells p993

John Stingl, Peter Eirew, Ian Ricketson, Mark Shackleton, François Vaillant, David Choi, Haiyan I. Li and Connie J. Eaves

doi:10.1038/nature04496


Eisosomes mark static sites of endocytosis p998

Tobias C. Walther, Jason H. Brickner, Pablo S. Aguilar, Sebastián Bernales, Carlos Pantoja and Peter Walter

doi:10.1038/nature04472

See also: Editor's summary


A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria p1004

Till S. Voss, Julie Healer, Allison J. Marty, Michael F. Duffy, Jennifer K. Thompson, James G. Beeson, John C. Reeder, Brendan S. Crabb and Alan F. Cowman

doi:10.1038/nature04407

See also: Editor's summary | News and Views by Borst & Genest


Identification of pathways regulating cell size and cell-cycle progression by RNAi p1009

Mikael Björklund, Minna Taipale, Markku Varjosalo, Juha Saharinen, Juhani Lahdenperä and Jussi Taipale

doi:10.1038/nature04469

See also: Editor's summary


Corrigendum: Genetic and developmental basis of evolutionary pelvic reduction in threespine sticklebacks p1014

Michael D. Shapiro, Melissa E. Marks, Catherine L. Peichel, Benjamin K. Blackman, Kirsten S. Nereng, Bjarni Jónsson, Dolph Schluter and David M. Kingsley

doi:10.1038/nature04500


Corrigendum: Genomic perspectives in microbial oceanography p1014

Edward F. DeLong and David M. Karl

doi:10.1038/nature04573


Corrigendum: Highly variable Northern Hemisphere temperatures reconstructed from low- and high-resolution proxy data p1014

Anders Moberg, Dmitry M. Sonechkin, Karin Holmgren, Nina M. Datsenko, Wibjörn Karlén and Stein-Erik Lauritzen

doi:10.1038/nature04575


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Technology Features

Protein purification: Fast forward p1017

Proteomics raises new challenges in protein purification. Technologies well adapted to isolate individual proteins get a makeover to tackle large numbers of samples. Laura Bonetta investigates.

Laura Bonetta

doi:10.1038/4391017a


Protein purification: Proteomics at Harvard p1017

doi:10.1038/4391017b


Protein purification: Protein purification for structural proteomics p1018

doi:10.1038/4391018a


Protein purification: Cell or cell-free? p1019

doi:10.1038/4391019a


Protein purification: Target identification p1021

doi:10.1038/4391021a


Protein purification: Table of suppliers p1022

doi:10.1038/4391022a


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Naturejobs

Prospect

Having it all p1025

A former researcher's career path shows how one can stay connected to academic science.

Paul Smaglik

doi:10.1038/nj7079-1025a


Region

Pacific sunrise p1026

The Pacific Northwest of North America doesn't just mean Microsoft, Intel and some big trees. Already noted for the quality of its biological research, the biotechnology base in cities such as Vancouver is set to grow too, as Virginia Gewin finds out.

Virginia Gewin

doi:10.1038/nj7079-1026a


Career Views

Neal Copeland and Nancy Jenkins, principal investigators, Institute of Molecular and Cell Biology, Singapore p1028

Husband-and-wife team venture overseas to start new cancer lab.

Janet Wright

doi:10.1038/nj7079-1028a


Learning to teach p1028

Oxford centre looks at whether improving teaching skills enhances research.

Keith Trigwell & Richard Arnold

doi:10.1038/nj7079-1028b


PhD, take two p1028

After a disappointing first attempt at a PhD, one grad student gets a new start.

Mhairi Dupre

doi:10.1038/nj7079-1028c


Highlights

California: Golden State Golden Opportunities

doi:10.1038/nj0112


Spotlight

Spotlight on Pacific Northwest

doi:10.1038/nj0113


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Futures

Don't imitate p1030

Wait for the real thing.

Gilles Amon

doi:10.1038/4391030a


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