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Nature 439, 546-548 (2 February 2006) | doi:10.1038/439546a; Published online 1 February 2006
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Neurobiology: Memories of a fruitfly
William G. Quinn1
Abstract
Despite its tiny size, the fruitfly brain is staggeringly intricate. So teasing apart how it remembers things — even a simple line pattern — is a daunting task. Progress is being made, thanks to genetic innovations.
Neuroscientists these days have a satisfactory understanding of how individual neurons work and of how they communicate with their immediate neighbours. By contrast, understanding at the next level of organization is hazier; for example, how neurons form functional circuits, how these circuits encode behaviour and particularly how experience changes the activity and connectivity in circuits to alter behaviour.
- William G. Quinn is in the Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.
Email: cquinn@mit.edu
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