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Nature 439, 23-24 (5 January 2006) | doi:10.1038/439023a; Published online 4 January 2006

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Developmental neuroscience: Two gradients are better than one

Liqun Luo1

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Wiring up retinal neurons to the correct brain region during development is a feat of precision growth. A novel directional cue repels retinal neuron fibres, acting as a counterbalance to a known attractive signal.

Our brain is made up of maps that organize what we sense. In the visual system, for example, an object is represented by the spatial activation pattern of retinal ganglion cells (RGCs), which form a two-dimensional sheet in the retina.

  1. Liqun Luo is in the Howard Hughes Medical Institute, Department of Biological Sciences, Stanford University, Stanford, California 94305, USA.
    Email: lluo@stanford.edu

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